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Anti-BI2L1/ BAIAP2L1/ IRTKS monoclonal antibody
Anti-BI2L1/ BAIAP2L1/ IRTKS antibody for FACS & in-vivo assay
Go to BAIAP2L1/BAIAP2L1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2016-Ab-1/ GM-Tg-hg-MP2016-Ab-2 | Anti-Human BAIAP2L1 monoclonal antibody | Human |
| GM-Tg-rg-MP2016-Ab-1/ GM-Tg-rg-MP2016-Ab-2 | Anti-Rat BAIAP2L1 monoclonal antibody | Rat |
| GM-Tg-mg-MP2016-Ab-1/ GM-Tg-mg-MP2016-Ab-2 | Anti-Mouse BAIAP2L1 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2016-Ab-1/ GM-Tg-cynog-MP2016-Ab-2 | Anti-Cynomolgus/ Rhesus macaque BAIAP2L1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2016-Ab-1/ GM-Tg-felg-MP2016-Ab-2 | Anti-Feline BAIAP2L1 monoclonal antibody | Feline |
| GM-Tg-cang-MP2016-Ab-1/ GM-Tg-cang-MP2016-Ab-2 | Anti-Canine BAIAP2L1 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2016-Ab-1/ GM-Tg-bovg-MP2016-Ab-2 | Anti-Bovine BAIAP2L1 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2016-Ab-1/ GM-Tg-equg-MP2016-Ab-2 | Anti-Equine BAIAP2L1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2016-Ab-1/ GM-Tg-hg-MP2016-Ab-2; GM-Tg-rg-MP2016-Ab-1/ GM-Tg-rg-MP2016-Ab-2; GM-Tg-mg-MP2016-Ab-1/ GM-Tg-mg-MP2016-Ab-2; GM-Tg-cynog-MP2016-Ab-1/ GM-Tg-cynog-MP2016-Ab-2; GM-Tg-felg-MP2016-Ab-1/ GM-Tg-felg-MP2016-Ab-2; GM-Tg-cang-MP2016-Ab-1/ GM-Tg-cang-MP2016-Ab-2; GM-Tg-bovg-MP2016-Ab-1/ GM-Tg-bovg-MP2016-Ab-2; GM-Tg-equg-MP2016-Ab-1/ GM-Tg-equg-MP2016-Ab-2 |
| Products Name | Anti-BAIAP2L1 monoclonal antibody |
| Format | mab |
| Target Name | BAIAP2L1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-BAIAP2L1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species BI2L1/ BAIAP2L1/ IRTKS VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP004377 | human BAIAP2L1 Lentivirus particle |
| ORF Viral Vector | pGMLP004377 | human BAIAP2L1 Lentivirus plasmid |
Target information
| Target ID | GM-MP2016 |
| Target Name | BAIAP2L1 |
| Gene ID | 55971,66898,304282,718278,479748,101098023,615412,100062881 |
| Gene Symbol and Synonyms | 1300006M19Rik,BAIAP2L1,IRTKS,RGD1308452 |
| Uniprot Accession | Q9UHR4,Q3KR97 |
| Uniprot Entry Name | BI2L1_HUMAN,BI2L1_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000006453 |
| Target Classification | N/A |
The target: BAIAP2L1, gene name: BAIAP2L1, also named as IRTKS. This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation. [provided by RefSeq, Oct 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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