Anti-BCORL/ BCORL1/ BCoR-L1 monoclonal antibody

Anti-BCORL/ BCORL1/ BCoR-L1 antibody for FACS & in-vivo assay

Target products collectionGo to BCORL1/BCORL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2019-Ab-1/ GM-Tg-hg-MP2019-Ab-2Anti-Human BCORL1 monoclonal antibodyHuman
GM-Tg-rg-MP2019-Ab-1/ GM-Tg-rg-MP2019-Ab-2Anti-Rat BCORL1 monoclonal antibodyRat
GM-Tg-mg-MP2019-Ab-1/ GM-Tg-mg-MP2019-Ab-2Anti-Mouse BCORL1 monoclonal antibodyMouse
GM-Tg-cynog-MP2019-Ab-1/ GM-Tg-cynog-MP2019-Ab-2Anti-Cynomolgus/ Rhesus macaque BCORL1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2019-Ab-1/ GM-Tg-felg-MP2019-Ab-2Anti-Feline BCORL1 monoclonal antibodyFeline
GM-Tg-cang-MP2019-Ab-1/ GM-Tg-cang-MP2019-Ab-2Anti-Canine BCORL1 monoclonal antibodyCanine
GM-Tg-bovg-MP2019-Ab-1/ GM-Tg-bovg-MP2019-Ab-2Anti-Bovine BCORL1 monoclonal antibodyBovine
GM-Tg-equg-MP2019-Ab-1/ GM-Tg-equg-MP2019-Ab-2Anti-Equine BCORL1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2019-Ab-1/ GM-Tg-hg-MP2019-Ab-2; GM-Tg-rg-MP2019-Ab-1/ GM-Tg-rg-MP2019-Ab-2;
GM-Tg-mg-MP2019-Ab-1/ GM-Tg-mg-MP2019-Ab-2; GM-Tg-cynog-MP2019-Ab-1/ GM-Tg-cynog-MP2019-Ab-2;
GM-Tg-felg-MP2019-Ab-1/ GM-Tg-felg-MP2019-Ab-2; GM-Tg-cang-MP2019-Ab-1/ GM-Tg-cang-MP2019-Ab-2;
GM-Tg-bovg-MP2019-Ab-1/ GM-Tg-bovg-MP2019-Ab-2; GM-Tg-equg-MP2019-Ab-1/ GM-Tg-equg-MP2019-Ab-2
Products NameAnti-BCORL1 monoclonal antibody
Formatmab
Target NameBCORL1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-BCORL1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species BCORL/ BCORL1/ BCoR-L1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2019
    Target NameBCORL1
    Gene ID63035,320376,302810,702657,481047,101081199,540023,100054632
    Gene Symbol and Synonyms6720425J07Rik,B930011H20Rik,BCoR-L1,BCORL1,CXorf10,RGD1566108,SHUVER
    Uniprot AccessionQ5H9F3
    Uniprot Entry NameBCORL_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000085185
    Target ClassificationN/A

    The target: BCORL1, gene name: BCORL1, also named as BCoR-L1, CXorf10. The protein encoded by this gene is a transcriptional corepressor that is found tethered to promoter regions by DNA-binding proteins. The encoded protein can interact with several different class II histone deacetylases to repress transcription. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.