Anti-BICD2/ SMALED2/ bA526D8.1 monoclonal antibody

Anti-BICD2/ SMALED2/ bA526D8.1 antibody for FACS & in-vivo assay

Target products collectionGo to BICD2/BICD2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2022-Ab-1/ GM-Tg-hg-MP2022-Ab-2Anti-Human BICD2 monoclonal antibodyHuman
GM-Tg-rg-MP2022-Ab-1/ GM-Tg-rg-MP2022-Ab-2Anti-Rat BICD2 monoclonal antibodyRat
GM-Tg-mg-MP2022-Ab-1/ GM-Tg-mg-MP2022-Ab-2Anti-Mouse BICD2 monoclonal antibodyMouse
GM-Tg-cynog-MP2022-Ab-1/ GM-Tg-cynog-MP2022-Ab-2Anti-Cynomolgus/ Rhesus macaque BICD2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2022-Ab-1/ GM-Tg-felg-MP2022-Ab-2Anti-Feline BICD2 monoclonal antibodyFeline
GM-Tg-cang-MP2022-Ab-1/ GM-Tg-cang-MP2022-Ab-2Anti-Canine BICD2 monoclonal antibodyCanine
GM-Tg-bovg-MP2022-Ab-1/ GM-Tg-bovg-MP2022-Ab-2Anti-Bovine BICD2 monoclonal antibodyBovine
GM-Tg-equg-MP2022-Ab-1/ GM-Tg-equg-MP2022-Ab-2Anti-Equine BICD2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2022-Ab-1/ GM-Tg-hg-MP2022-Ab-2; GM-Tg-rg-MP2022-Ab-1/ GM-Tg-rg-MP2022-Ab-2;
GM-Tg-mg-MP2022-Ab-1/ GM-Tg-mg-MP2022-Ab-2; GM-Tg-cynog-MP2022-Ab-1/ GM-Tg-cynog-MP2022-Ab-2;
GM-Tg-felg-MP2022-Ab-1/ GM-Tg-felg-MP2022-Ab-2; GM-Tg-cang-MP2022-Ab-1/ GM-Tg-cang-MP2022-Ab-2;
GM-Tg-bovg-MP2022-Ab-1/ GM-Tg-bovg-MP2022-Ab-2; GM-Tg-equg-MP2022-Ab-1/ GM-Tg-equg-MP2022-Ab-2
Products NameAnti-BICD2 monoclonal antibody
Formatmab
Target NameBICD2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-BICD2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species BICD2/ SMALED2/ bA526D8.1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2022
    Target NameBICD2
    Gene ID23299,76895,306809,706621,484214,123378901,282447,100056101
    Gene Symbol and SynonymsbA526D8.1,BICD2,SMALED2,SMALED2A,SMALED2B
    Uniprot AccessionQ8TD16
    Uniprot Entry NameBICD2_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000185963
    Target ClassificationN/A

    The target: BICD2, gene name: BICD2, also named as SMALED2, bA526D8.1. This gene is one of two human homologs of Drosophila bicaudal-D and a member of the Bicoid family. It has been implicated in dynein-mediated, minus end-directed motility along microtubules. It has also been reported to be a phosphorylation target of NIMA related kinase 8. Two alternative splice variants have been described. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.