Anti-CF418/ C8orf37/ BBS21 monoclonal antibody

Anti-CF418/ C8orf37/ BBS21 antibody for FACS & in-vivo assay

Target products collectionGo to C8orf37/C8orf37 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2030-Ab-1/ GM-Tg-hg-MP2030-Ab-2Anti-Human C8orf37 monoclonal antibodyHuman
GM-Tg-rg-MP2030-Ab-1/ GM-Tg-rg-MP2030-Ab-2Anti-Rat C8orf37 monoclonal antibodyRat
GM-Tg-mg-MP2030-Ab-1/ GM-Tg-mg-MP2030-Ab-2Anti-Mouse C8orf37 monoclonal antibodyMouse
GM-Tg-cynog-MP2030-Ab-1/ GM-Tg-cynog-MP2030-Ab-2Anti-Cynomolgus/ Rhesus macaque C8orf37 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2030-Ab-1/ GM-Tg-felg-MP2030-Ab-2Anti-Feline C8orf37 monoclonal antibodyFeline
GM-Tg-cang-MP2030-Ab-1/ GM-Tg-cang-MP2030-Ab-2Anti-Canine C8orf37 monoclonal antibodyCanine
GM-Tg-bovg-MP2030-Ab-1/ GM-Tg-bovg-MP2030-Ab-2Anti-Bovine C8orf37 monoclonal antibodyBovine
GM-Tg-equg-MP2030-Ab-1/ GM-Tg-equg-MP2030-Ab-2Anti-Equine C8orf37 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2030-Ab-1/ GM-Tg-hg-MP2030-Ab-2; GM-Tg-rg-MP2030-Ab-1/ GM-Tg-rg-MP2030-Ab-2;
GM-Tg-mg-MP2030-Ab-1/ GM-Tg-mg-MP2030-Ab-2; GM-Tg-cynog-MP2030-Ab-1/ GM-Tg-cynog-MP2030-Ab-2;
GM-Tg-felg-MP2030-Ab-1/ GM-Tg-felg-MP2030-Ab-2; GM-Tg-cang-MP2030-Ab-1/ GM-Tg-cang-MP2030-Ab-2;
GM-Tg-bovg-MP2030-Ab-1/ GM-Tg-bovg-MP2030-Ab-2; GM-Tg-equg-MP2030-Ab-1/ GM-Tg-equg-MP2030-Ab-2
Products NameAnti-C8orf37 monoclonal antibody
Formatmab
Target NameC8orf37
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-C8orf37 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CF418/ C8orf37/ BBS21 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2030
    Target NameC8orf37
    Gene ID157657,67157,362483,700877,611815,101090332,614744,100055428
    Gene Symbol and Synonyms2610301B20Rik,BBS21,C14H8orf37,C29H8orf37,C8H8orf37,C8orf37,C9H8orf37,CF2H8orf37,CFAP418,CORD16,FAP418,MOT25,RP64,smalltalk
    Uniprot AccessionQ96NL8,Q6AY71,E1BC52
    Uniprot Entry NameCF418_HUMAN,CF418_RAT,CF418_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000156172
    Target ClassificationN/A

    The target: C8orf37, gene name: C8orf37, also named as BBS21, CORD16, RP64, smalltalk. This gene encodes a ubiquitously expressed protein of unknown function. It has high levels of mRNA expression in the brain, heart, and retina and the protein co-localizes with polyglutamylated tubulin at the base of the primary cilium in human retinal pigment epithelial cells. Mutations in this gene have been associated with autosomal recessive cone-rod dystrophy (arCRD) and retinitis pigmentosa (arRP). [provided by RefSeq, Mar 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.