Anti-CAP2 monoclonal antibody

Anti-CAP2 antibody for FACS & in-vivo assay

Target products collectionGo to CAP2/CAP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2032-Ab-1/ GM-Tg-hg-MP2032-Ab-2Anti-Human CAP2 monoclonal antibodyHuman
GM-Tg-rg-MP2032-Ab-1/ GM-Tg-rg-MP2032-Ab-2Anti-Rat CAP2 monoclonal antibodyRat
GM-Tg-mg-MP2032-Ab-1/ GM-Tg-mg-MP2032-Ab-2Anti-Mouse CAP2 monoclonal antibodyMouse
GM-Tg-cynog-MP2032-Ab-1/ GM-Tg-cynog-MP2032-Ab-2Anti-Cynomolgus/ Rhesus macaque CAP2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2032-Ab-1/ GM-Tg-felg-MP2032-Ab-2Anti-Feline CAP2 monoclonal antibodyFeline
GM-Tg-cang-MP2032-Ab-1/ GM-Tg-cang-MP2032-Ab-2Anti-Canine CAP2 monoclonal antibodyCanine
GM-Tg-bovg-MP2032-Ab-1/ GM-Tg-bovg-MP2032-Ab-2Anti-Bovine CAP2 monoclonal antibodyBovine
GM-Tg-equg-MP2032-Ab-1/ GM-Tg-equg-MP2032-Ab-2Anti-Equine CAP2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2032-Ab-1/ GM-Tg-hg-MP2032-Ab-2; GM-Tg-rg-MP2032-Ab-1/ GM-Tg-rg-MP2032-Ab-2;
GM-Tg-mg-MP2032-Ab-1/ GM-Tg-mg-MP2032-Ab-2; GM-Tg-cynog-MP2032-Ab-1/ GM-Tg-cynog-MP2032-Ab-2;
GM-Tg-felg-MP2032-Ab-1/ GM-Tg-felg-MP2032-Ab-2; GM-Tg-cang-MP2032-Ab-1/ GM-Tg-cang-MP2032-Ab-2;
GM-Tg-bovg-MP2032-Ab-1/ GM-Tg-bovg-MP2032-Ab-2; GM-Tg-equg-MP2032-Ab-1/ GM-Tg-equg-MP2032-Ab-2
Products NameAnti-CAP2 monoclonal antibody
Formatmab
Target NameCAP2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CAP2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CAP2 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm004197mouse Cap2 Lentivirus plasmid
    ORF Viral VectorvGMLPm004197mouse Cap2 Lentivirus particle


    Target information

    Target IDGM-MP2032
    Target NameCAP2
    Gene ID10486,67252,116653,703445,478731,101100390,515190,100052005
    Gene Symbol and Synonyms2810452G09Rik,CAP2
    Uniprot AccessionP40123,P52481
    Uniprot Entry NameCAP2_HUMAN,CAP2_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000112186
    Target ClassificationN/A

    The target: CAP2, gene name: CAP2, also named as . This gene was identified by its similarity to the gene for human adenylyl cyclase-associated protein. The function of the protein encoded by this gene is unknown. However, the protein appears to be able to interact with adenylyl cyclase-associated protein and actin. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.