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Anti-CCNT2/ CYCT2 monoclonal antibody
Anti-CCNT2/ CYCT2 antibody for FACS & in-vivo assay
Go to CCNT2/CCNT2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2040-Ab-1/ GM-Tg-hg-MP2040-Ab-2 | Anti-Human CCNT2 monoclonal antibody | Human |
| GM-Tg-rg-MP2040-Ab-1/ GM-Tg-rg-MP2040-Ab-2 | Anti-Rat CCNT2 monoclonal antibody | Rat |
| GM-Tg-mg-MP2040-Ab-1/ GM-Tg-mg-MP2040-Ab-2 | Anti-Mouse CCNT2 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2040-Ab-1/ GM-Tg-cynog-MP2040-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CCNT2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2040-Ab-1/ GM-Tg-felg-MP2040-Ab-2 | Anti-Feline CCNT2 monoclonal antibody | Feline |
| GM-Tg-cang-MP2040-Ab-1/ GM-Tg-cang-MP2040-Ab-2 | Anti-Canine CCNT2 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2040-Ab-1/ GM-Tg-bovg-MP2040-Ab-2 | Anti-Bovine CCNT2 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2040-Ab-1/ GM-Tg-equg-MP2040-Ab-2 | Anti-Equine CCNT2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2040-Ab-1/ GM-Tg-hg-MP2040-Ab-2; GM-Tg-rg-MP2040-Ab-1/ GM-Tg-rg-MP2040-Ab-2; GM-Tg-mg-MP2040-Ab-1/ GM-Tg-mg-MP2040-Ab-2; GM-Tg-cynog-MP2040-Ab-1/ GM-Tg-cynog-MP2040-Ab-2; GM-Tg-felg-MP2040-Ab-1/ GM-Tg-felg-MP2040-Ab-2; GM-Tg-cang-MP2040-Ab-1/ GM-Tg-cang-MP2040-Ab-2; GM-Tg-bovg-MP2040-Ab-1/ GM-Tg-bovg-MP2040-Ab-2; GM-Tg-equg-MP2040-Ab-1/ GM-Tg-equg-MP2040-Ab-2 |
| Products Name | Anti-CCNT2 monoclonal antibody |
| Format | mab |
| Target Name | CCNT2 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CCNT2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species CCNT2/ CYCT2 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP2040 |
| Target Name | CCNT2 |
| Gene ID | 905,72949,304758,708813,476126,101088946,521089,100050510 |
| Gene Symbol and Synonyms | 2900041I18Rik,CCNT2,CYCT2,CycT2a,CycT2b |
| Uniprot Accession | O60583 |
| Uniprot Entry Name | CCNT2_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000082258 |
| Target Classification | N/A |
The target: CCNT2, gene name: CCNT2, also named as CYCT2. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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