Anti-CDK16/ PCTAIRE/ PCTAIRE1 monoclonal antibody

Anti-CDK16/ PCTAIRE/ PCTAIRE1 antibody for FACS & in-vivo assay

Target products collectionGo to CDK16/CDK16 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2047-Ab-1/ GM-Tg-hg-MP2047-Ab-2Anti-Human CDK16 monoclonal antibodyHuman
GM-Tg-rg-MP2047-Ab-1/ GM-Tg-rg-MP2047-Ab-2Anti-Rat CDK16 monoclonal antibodyRat
GM-Tg-mg-MP2047-Ab-1/ GM-Tg-mg-MP2047-Ab-2Anti-Mouse CDK16 monoclonal antibodyMouse
GM-Tg-cynog-MP2047-Ab-1/ GM-Tg-cynog-MP2047-Ab-2Anti-Cynomolgus/ Rhesus macaque CDK16 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2047-Ab-1/ GM-Tg-felg-MP2047-Ab-2Anti-Feline CDK16 monoclonal antibodyFeline
GM-Tg-cang-MP2047-Ab-1/ GM-Tg-cang-MP2047-Ab-2Anti-Canine CDK16 monoclonal antibodyCanine
GM-Tg-bovg-MP2047-Ab-1/ GM-Tg-bovg-MP2047-Ab-2Anti-Bovine CDK16 monoclonal antibodyBovine
GM-Tg-equg-MP2047-Ab-1/ GM-Tg-equg-MP2047-Ab-2Anti-Equine CDK16 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2047-Ab-1/ GM-Tg-hg-MP2047-Ab-2; GM-Tg-rg-MP2047-Ab-1/ GM-Tg-rg-MP2047-Ab-2;
GM-Tg-mg-MP2047-Ab-1/ GM-Tg-mg-MP2047-Ab-2; GM-Tg-cynog-MP2047-Ab-1/ GM-Tg-cynog-MP2047-Ab-2;
GM-Tg-felg-MP2047-Ab-1/ GM-Tg-felg-MP2047-Ab-2; GM-Tg-cang-MP2047-Ab-1/ GM-Tg-cang-MP2047-Ab-2;
GM-Tg-bovg-MP2047-Ab-1/ GM-Tg-bovg-MP2047-Ab-2; GM-Tg-equg-MP2047-Ab-1/ GM-Tg-equg-MP2047-Ab-2
Products NameAnti-CDK16 monoclonal antibody
Formatmab
Target NameCDK16
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CDK16 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CDK16/ PCTAIRE/ PCTAIRE1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm005443mouse Cdk16 Lentivirus plasmid
    ORF Viral VectorvGMLPm005443mouse Cdk16 Lentivirus particle


    Target information

    Target IDGM-MP2047
    Target NameCDK16
    Gene ID5127,18555,81741,712033,480897,101094653,613810,100060831
    Gene Symbol and SynonymsCDK16,Crk5,PCTAIRE,PCTAIRE1,PCTGAIRE,PCTK1
    Uniprot AccessionQ00536,Q63686
    Uniprot Entry NameCDK16_HUMAN,CDK16_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseProstate Cancer
    Gene EnsemblENSG00000102225
    Target ClassificationKinase

    The target: CDK16, gene name: CDK16, also named as PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1. The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.