Anti-CEP55/ C10orf3/ CT111 monoclonal antibody

Anti-CEP55/ C10orf3/ CT111 antibody for FACS & in-vivo assay

Target products collectionGo to CEP55/CEP55 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2051-Ab-1/ GM-Tg-hg-MP2051-Ab-2Anti-Human CEP55 monoclonal antibodyHuman
GM-Tg-rg-MP2051-Ab-1/ GM-Tg-rg-MP2051-Ab-2Anti-Rat CEP55 monoclonal antibodyRat
GM-Tg-mg-MP2051-Ab-1/ GM-Tg-mg-MP2051-Ab-2Anti-Mouse CEP55 monoclonal antibodyMouse
GM-Tg-cynog-MP2051-Ab-1/ GM-Tg-cynog-MP2051-Ab-2Anti-Cynomolgus/ Rhesus macaque CEP55 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2051-Ab-1/ GM-Tg-felg-MP2051-Ab-2Anti-Feline CEP55 monoclonal antibodyFeline
GM-Tg-cang-MP2051-Ab-1/ GM-Tg-cang-MP2051-Ab-2Anti-Canine CEP55 monoclonal antibodyCanine
GM-Tg-bovg-MP2051-Ab-1/ GM-Tg-bovg-MP2051-Ab-2Anti-Bovine CEP55 monoclonal antibodyBovine
GM-Tg-equg-MP2051-Ab-1/ GM-Tg-equg-MP2051-Ab-2Anti-Equine CEP55 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2051-Ab-1/ GM-Tg-hg-MP2051-Ab-2; GM-Tg-rg-MP2051-Ab-1/ GM-Tg-rg-MP2051-Ab-2;
GM-Tg-mg-MP2051-Ab-1/ GM-Tg-mg-MP2051-Ab-2; GM-Tg-cynog-MP2051-Ab-1/ GM-Tg-cynog-MP2051-Ab-2;
GM-Tg-felg-MP2051-Ab-1/ GM-Tg-felg-MP2051-Ab-2; GM-Tg-cang-MP2051-Ab-1/ GM-Tg-cang-MP2051-Ab-2;
GM-Tg-bovg-MP2051-Ab-1/ GM-Tg-bovg-MP2051-Ab-2; GM-Tg-equg-MP2051-Ab-1/ GM-Tg-equg-MP2051-Ab-2
Products NameAnti-CEP55 monoclonal antibody
Formatmab
Target NameCEP55
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CEP55 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CEP55/ C10orf3/ CT111 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm004859mouse Cep55 Lentivirus plasmid
    ORF Viral VectorvGMLPm004859mouse Cep55 Lentivirus particle


    Target information

    Target IDGM-MP2051
    Target NameCEP55
    Gene ID55165,74107,294074,699890,477773,101094136,513594,100071184
    Gene Symbol and Synonyms1200008O12Rik,2700032M20Rik,C10orf3,CEP55,CT111,MARCH,RGD1305340,URCC6
    Uniprot AccessionQ53EZ4,Q4V7C8
    Uniprot Entry NameCEP55_HUMAN,CEP55_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseBreast Cancer
    Gene EnsemblENSG00000138180
    Target ClassificationN/A

    The target: CEP55, gene name: CEP55, also named as C10orf3, CT111, MARCH, URCC6. Enables identical protein binding activity. Involved in cranial skeletal system development; establishment of protein localization; and midbody abscission. Acts upstream of or within mitotic cytokinesis. Located in Flemming body; centriolar satellite; and plasma membrane. Implicated in multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia and hydranencephaly. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.