Anti-CF157/ CFAP157/ C9orf117 monoclonal antibody

Anti-CF157/ CFAP157/ C9orf117 antibody for FACS & in-vivo assay

Target products collectionGo to CFAP157/CFAP157 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2053-Ab-1/ GM-Tg-hg-MP2053-Ab-2Anti-Human CFAP157 monoclonal antibodyHuman
GM-Tg-rg-MP2053-Ab-1/ GM-Tg-rg-MP2053-Ab-2Anti-Rat CFAP157 monoclonal antibodyRat
GM-Tg-mg-MP2053-Ab-1/ GM-Tg-mg-MP2053-Ab-2Anti-Mouse CFAP157 monoclonal antibodyMouse
GM-Tg-cynog-MP2053-Ab-1/ GM-Tg-cynog-MP2053-Ab-2Anti-Cynomolgus/ Rhesus macaque CFAP157 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2053-Ab-1/ GM-Tg-felg-MP2053-Ab-2Anti-Feline CFAP157 monoclonal antibodyFeline
GM-Tg-cang-MP2053-Ab-1/ GM-Tg-cang-MP2053-Ab-2Anti-Canine CFAP157 monoclonal antibodyCanine
GM-Tg-bovg-MP2053-Ab-1/ GM-Tg-bovg-MP2053-Ab-2Anti-Bovine CFAP157 monoclonal antibodyBovine
GM-Tg-equg-MP2053-Ab-1/ GM-Tg-equg-MP2053-Ab-2Anti-Equine CFAP157 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2053-Ab-1/ GM-Tg-hg-MP2053-Ab-2; GM-Tg-rg-MP2053-Ab-1/ GM-Tg-rg-MP2053-Ab-2;
GM-Tg-mg-MP2053-Ab-1/ GM-Tg-mg-MP2053-Ab-2; GM-Tg-cynog-MP2053-Ab-1/ GM-Tg-cynog-MP2053-Ab-2;
GM-Tg-felg-MP2053-Ab-1/ GM-Tg-felg-MP2053-Ab-2; GM-Tg-cang-MP2053-Ab-1/ GM-Tg-cang-MP2053-Ab-2;
GM-Tg-bovg-MP2053-Ab-1/ GM-Tg-bovg-MP2053-Ab-2; GM-Tg-equg-MP2053-Ab-1/ GM-Tg-equg-MP2053-Ab-2
Products NameAnti-CFAP157 monoclonal antibody
Formatmab
Target NameCFAP157
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CFAP157 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CF157/ CFAP157/ C9orf117 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2053
    Target NameCFAP157
    Gene ID286207,227736,499781,706872,480714,101097026,617116,100070483
    Gene Symbol and Synonyms1700019L03Rik,C11H9orf117,C15H9orf117,C25H9orf117,C9H9orf117,C9orf117,CFAP157
    Uniprot AccessionQ5JU67,Q4V7B0
    Uniprot Entry NameCF157_HUMAN,CF157_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000160401
    Target ClassificationN/A

    The target: CFAP157, gene name: CFAP157, also named as C9orf117. Predicted to enable microtubule binding activity. Predicted to be involved in sperm axoneme assembly. Located in cytosol; intracellular membrane-bounded organelle; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.