Anti-COPRS/ C17orf79/ COPR5 monoclonal antibody

Anti-COPRS/ C17orf79/ COPR5 antibody for FACS & in-vivo assay

Target products collectionGo to COPRS/COPRS products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2063-Ab-1/ GM-Tg-hg-MP2063-Ab-2Anti-Human COPRS monoclonal antibodyHuman
GM-Tg-rg-MP2063-Ab-1/ GM-Tg-rg-MP2063-Ab-2Anti-Rat COPRS monoclonal antibodyRat
GM-Tg-mg-MP2063-Ab-1/ GM-Tg-mg-MP2063-Ab-2Anti-Mouse COPRS monoclonal antibodyMouse
GM-Tg-cynog-MP2063-Ab-1/ GM-Tg-cynog-MP2063-Ab-2Anti-Cynomolgus/ Rhesus macaque COPRS monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2063-Ab-1/ GM-Tg-felg-MP2063-Ab-2Anti-Feline COPRS monoclonal antibodyFeline
GM-Tg-cang-MP2063-Ab-1/ GM-Tg-cang-MP2063-Ab-2Anti-Canine COPRS monoclonal antibodyCanine
GM-Tg-bovg-MP2063-Ab-1/ GM-Tg-bovg-MP2063-Ab-2Anti-Bovine COPRS monoclonal antibodyBovine
GM-Tg-equg-MP2063-Ab-1/ GM-Tg-equg-MP2063-Ab-2Anti-Equine COPRS monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2063-Ab-1/ GM-Tg-hg-MP2063-Ab-2; GM-Tg-rg-MP2063-Ab-1/ GM-Tg-rg-MP2063-Ab-2;
GM-Tg-mg-MP2063-Ab-1/ GM-Tg-mg-MP2063-Ab-2; GM-Tg-cynog-MP2063-Ab-1/ GM-Tg-cynog-MP2063-Ab-2;
GM-Tg-felg-MP2063-Ab-1/ GM-Tg-felg-MP2063-Ab-2; GM-Tg-cang-MP2063-Ab-1/ GM-Tg-cang-MP2063-Ab-2;
GM-Tg-bovg-MP2063-Ab-1/ GM-Tg-bovg-MP2063-Ab-2; GM-Tg-equg-MP2063-Ab-1/ GM-Tg-equg-MP2063-Ab-2
Products NameAnti-COPRS monoclonal antibody
Formatmab
Target NameCOPRS
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-COPRS benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species COPRS/ C17orf79/ COPR5 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2063
    Target NameCOPRS
    Gene ID55352,66423,290925,713293,480617,101092902,506999,100071846
    Gene Symbol and Synonyms1700029I03Rik,2410022L05Rik,C17orf79,C19H17orf79,C9H17orf79,CE1H17orf79,COPR5,COPRS,HSA272196,RGD1565675,TTP1
    Uniprot AccessionQ9NQ92,A5PJD3
    Uniprot Entry NameCOPRS_HUMAN,COPRS_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000172301
    Target ClassificationN/A

    The target: COPRS, gene name: COPRS, also named as C17orf79, COPR5, HSA272196, TTP1. Enables histone binding activity. Involved in histone H4-R3 methylation. Located in cytosol; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.