Anti-CSDE1/ D1S155E/ UNR monoclonal antibody

Anti-CSDE1/ D1S155E/ UNR antibody for FACS & in-vivo assay

Target products collectionGo to CSDE1/CSDE1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2068-Ab-1/ GM-Tg-hg-MP2068-Ab-2Anti-Human CSDE1 monoclonal antibodyHuman
GM-Tg-rg-MP2068-Ab-1/ GM-Tg-rg-MP2068-Ab-2Anti-Rat CSDE1 monoclonal antibodyRat
GM-Tg-mg-MP2068-Ab-1/ GM-Tg-mg-MP2068-Ab-2Anti-Mouse CSDE1 monoclonal antibodyMouse
GM-Tg-cynog-MP2068-Ab-1/ GM-Tg-cynog-MP2068-Ab-2Anti-Cynomolgus/ Rhesus macaque CSDE1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2068-Ab-1/ GM-Tg-felg-MP2068-Ab-2Anti-Feline CSDE1 monoclonal antibodyFeline
GM-Tg-cang-MP2068-Ab-1/ GM-Tg-cang-MP2068-Ab-2Anti-Canine CSDE1 monoclonal antibodyCanine
GM-Tg-bovg-MP2068-Ab-1/ GM-Tg-bovg-MP2068-Ab-2Anti-Bovine CSDE1 monoclonal antibodyBovine
GM-Tg-equg-MP2068-Ab-1/ GM-Tg-equg-MP2068-Ab-2Anti-Equine CSDE1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2068-Ab-1/ GM-Tg-hg-MP2068-Ab-2; GM-Tg-rg-MP2068-Ab-1/ GM-Tg-rg-MP2068-Ab-2;
GM-Tg-mg-MP2068-Ab-1/ GM-Tg-mg-MP2068-Ab-2; GM-Tg-cynog-MP2068-Ab-1/ GM-Tg-cynog-MP2068-Ab-2;
GM-Tg-felg-MP2068-Ab-1/ GM-Tg-felg-MP2068-Ab-2; GM-Tg-cang-MP2068-Ab-1/ GM-Tg-cang-MP2068-Ab-2;
GM-Tg-bovg-MP2068-Ab-1/ GM-Tg-bovg-MP2068-Ab-2; GM-Tg-equg-MP2068-Ab-1/ GM-Tg-equg-MP2068-Ab-2
Products NameAnti-CSDE1 monoclonal antibody
Formatmab
Target NameCSDE1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CSDE1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CSDE1/ D1S155E/ UNR VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm004105mouse Csde1 Lentivirus plasmid
    ORF Viral VectorvGMLPm004105mouse Csde1 Lentivirus particle


    Target information

    Target IDGM-MP2068
    Target NameCSDE1
    Gene ID7812,229663,117180,708897,475807,101098614,513993,100065444
    Gene Symbol and SynonymsCSDE1,D1S155E,D3Jfr1,mKIAA0885,UNR
    Uniprot AccessionO75534,P18395
    Uniprot Entry NameCSDE1_HUMAN,CSDE1_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000009307
    Target ClassificationN/A

    The target: CSDE1, gene name: CSDE1, also named as D1S155E, UNR. Enables RNA stem-loop binding activity. Involved in IRES-dependent viral translational initiation; nuclear-transcribed mRNA catabolic process, no-go decay; and stress granule assembly. Located in Golgi apparatus; cytosol; and plasma membrane. Part of CRD-mediated mRNA stability complex. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.