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Anti-CTNA1/ CTNNA1/ CAP102 monoclonal antibody
Anti-CTNA1/ CTNNA1/ CAP102 antibody for FACS & in-vivo assay
Go to CTNNA1/CTNNA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2069-Ab-1/ GM-Tg-hg-MP2069-Ab-2 | Anti-Human CTNNA1 monoclonal antibody | Human |
| GM-Tg-rg-MP2069-Ab-1/ GM-Tg-rg-MP2069-Ab-2 | Anti-Rat CTNNA1 monoclonal antibody | Rat |
| GM-Tg-mg-MP2069-Ab-1/ GM-Tg-mg-MP2069-Ab-2 | Anti-Mouse CTNNA1 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2069-Ab-1/ GM-Tg-cynog-MP2069-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CTNNA1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2069-Ab-1/ GM-Tg-felg-MP2069-Ab-2 | Anti-Feline CTNNA1 monoclonal antibody | Feline |
| GM-Tg-cang-MP2069-Ab-1/ GM-Tg-cang-MP2069-Ab-2 | Anti-Canine CTNNA1 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2069-Ab-1/ GM-Tg-bovg-MP2069-Ab-2 | Anti-Bovine CTNNA1 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2069-Ab-1/ GM-Tg-equg-MP2069-Ab-2 | Anti-Equine CTNNA1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2069-Ab-1/ GM-Tg-hg-MP2069-Ab-2; GM-Tg-rg-MP2069-Ab-1/ GM-Tg-rg-MP2069-Ab-2; GM-Tg-mg-MP2069-Ab-1/ GM-Tg-mg-MP2069-Ab-2; GM-Tg-cynog-MP2069-Ab-1/ GM-Tg-cynog-MP2069-Ab-2; GM-Tg-felg-MP2069-Ab-1/ GM-Tg-felg-MP2069-Ab-2; GM-Tg-cang-MP2069-Ab-1/ GM-Tg-cang-MP2069-Ab-2; GM-Tg-bovg-MP2069-Ab-1/ GM-Tg-bovg-MP2069-Ab-2; GM-Tg-equg-MP2069-Ab-1/ GM-Tg-equg-MP2069-Ab-2 |
| Products Name | Anti-CTNNA1 monoclonal antibody |
| Format | mab |
| Target Name | CTNNA1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CTNNA1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species CTNA1/ CTNNA1/ CAP102 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMAD000493 | human CTNNA1 Adenovirus plasmid |
| ORF Viral Vector | vGMAD000500 | human CTNNA1 Adenovirus particle |
| ORF Viral Vector | pGMAD000130 | human CTNNA1 Adenovirus plasmid |
| ORF Viral Vector | pGMAD000500 | human CTNNA1 Adenovirus plasmid |
| ORF Viral Vector | vGMAD000130 | human CTNNA1 Adenovirus particle |
| ORF Viral Vector | vGMAD000493 | human CTNNA1 Adenovirus particle |
| ORF Viral Vector | pGMLPm004028 | mouse Ctnna1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004028 | mouse Ctnna1 Lentivirus particle |
Target information
| Target ID | GM-MP2069 |
| Target Name | CTNNA1 |
| Gene ID | 1495,12385,307505,574385,474698,101089324,526848,100072548 |
| Gene Symbol and Synonyms | 2010010M04Rik,CAP102,Catna1,CTNNA1,MDBS2,MDPT2 |
| Uniprot Accession | P35221,Q3MHM6 |
| Uniprot Entry Name | CTNA1_HUMAN,CTNA1_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000044115 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: CTNNA1, gene name: CTNNA1, also named as CAP102, MDPT2. This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy. [provided by RefSeq, May 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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