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Anti-CTND1/ CTNND1/ BCDS2 monoclonal antibody
Anti-CTND1/ CTNND1/ BCDS2 antibody for FACS & in-vivo assay
Go to CTNND1/CTNND1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2070-Ab-1/ GM-Tg-hg-MP2070-Ab-2 | Anti-Human CTNND1 monoclonal antibody | Human |
| GM-Tg-rg-MP2070-Ab-1/ GM-Tg-rg-MP2070-Ab-2 | Anti-Rat CTNND1 monoclonal antibody | Rat |
| GM-Tg-mg-MP2070-Ab-1/ GM-Tg-mg-MP2070-Ab-2 | Anti-Mouse CTNND1 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2070-Ab-1/ GM-Tg-cynog-MP2070-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CTNND1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2070-Ab-1/ GM-Tg-felg-MP2070-Ab-2 | Anti-Feline CTNND1 monoclonal antibody | Feline |
| GM-Tg-cang-MP2070-Ab-1/ GM-Tg-cang-MP2070-Ab-2 | Anti-Canine CTNND1 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2070-Ab-1/ GM-Tg-bovg-MP2070-Ab-2 | Anti-Bovine CTNND1 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2070-Ab-1/ GM-Tg-equg-MP2070-Ab-2 | Anti-Equine CTNND1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2070-Ab-1/ GM-Tg-hg-MP2070-Ab-2; GM-Tg-rg-MP2070-Ab-1/ GM-Tg-rg-MP2070-Ab-2; GM-Tg-mg-MP2070-Ab-1/ GM-Tg-mg-MP2070-Ab-2; GM-Tg-cynog-MP2070-Ab-1/ GM-Tg-cynog-MP2070-Ab-2; GM-Tg-felg-MP2070-Ab-1/ GM-Tg-felg-MP2070-Ab-2; GM-Tg-cang-MP2070-Ab-1/ GM-Tg-cang-MP2070-Ab-2; GM-Tg-bovg-MP2070-Ab-1/ GM-Tg-bovg-MP2070-Ab-2; GM-Tg-equg-MP2070-Ab-1/ GM-Tg-equg-MP2070-Ab-2 |
| Products Name | Anti-CTNND1 monoclonal antibody |
| Format | mab |
| Target Name | CTNND1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-CTNND1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species CTND1/ CTNND1/ BCDS2 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLV000790 | human CTNND1 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000790 | human CTNND1 Lentivirus particle |
Target information
| Target ID | GM-MP2070 |
| Target Name | CTNND1 |
| Gene ID | 1500,12388,311163,704212,483489,101091972,515187,100067065 |
| Gene Symbol and Synonyms | BCDS2,CAS,Catns,CTNND,CTNND1,mKIAA0384,p120,p120(CAS),p120(CTN),P120CAS,P120CTN |
| Uniprot Accession | O60716 |
| Uniprot Entry Name | CTND1_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000198561 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: CTNND1, gene name: CTNND1, also named as BCDS2, CAS, CTNND, P120CAS, P120CTN, p120, p120(CAS), p120(CTN). This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (™X2) gene. [provided by RefSeq, Dec 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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