- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-DGKG/ DAGK3/ DGK-GAMMA monoclonal antibody
Anti-DGKG/ DAGK3/ DGK-GAMMA antibody for FACS & in-vivo assay
Go to DGKG/DGKG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2077-Ab-1/ GM-Tg-hg-MP2077-Ab-2 | Anti-Human DGKG monoclonal antibody | Human |
| GM-Tg-rg-MP2077-Ab-1/ GM-Tg-rg-MP2077-Ab-2 | Anti-Rat DGKG monoclonal antibody | Rat |
| GM-Tg-mg-MP2077-Ab-1/ GM-Tg-mg-MP2077-Ab-2 | Anti-Mouse DGKG monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2077-Ab-1/ GM-Tg-cynog-MP2077-Ab-2 | Anti-Cynomolgus/ Rhesus macaque DGKG monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2077-Ab-1/ GM-Tg-felg-MP2077-Ab-2 | Anti-Feline DGKG monoclonal antibody | Feline |
| GM-Tg-cang-MP2077-Ab-1/ GM-Tg-cang-MP2077-Ab-2 | Anti-Canine DGKG monoclonal antibody | Canine |
| GM-Tg-bovg-MP2077-Ab-1/ GM-Tg-bovg-MP2077-Ab-2 | Anti-Bovine DGKG monoclonal antibody | Bovine |
| GM-Tg-equg-MP2077-Ab-1/ GM-Tg-equg-MP2077-Ab-2 | Anti-Equine DGKG monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2077-Ab-1/ GM-Tg-hg-MP2077-Ab-2; GM-Tg-rg-MP2077-Ab-1/ GM-Tg-rg-MP2077-Ab-2; GM-Tg-mg-MP2077-Ab-1/ GM-Tg-mg-MP2077-Ab-2; GM-Tg-cynog-MP2077-Ab-1/ GM-Tg-cynog-MP2077-Ab-2; GM-Tg-felg-MP2077-Ab-1/ GM-Tg-felg-MP2077-Ab-2; GM-Tg-cang-MP2077-Ab-1/ GM-Tg-cang-MP2077-Ab-2; GM-Tg-bovg-MP2077-Ab-1/ GM-Tg-bovg-MP2077-Ab-2; GM-Tg-equg-MP2077-Ab-1/ GM-Tg-equg-MP2077-Ab-2 |
| Products Name | Anti-DGKG monoclonal antibody |
| Format | mab |
| Target Name | DGKG |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-DGKG benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species DGKG/ DAGK3/ DGK-GAMMA VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP2077 |
| Target Name | DGKG |
| Gene ID | 1608,110197,25666,699967,488115,101100829,518523,100067985 |
| Gene Symbol and Synonyms | 2900055E17Rik,90kDa,DAGK3,DGK-GAMMA,DGK-III,DGKG,DGKIII,E430001K23Rik,mKIAA4131 |
| Uniprot Accession | P49619,P49620 |
| Uniprot Entry Name | DGKG_HUMAN,DGKG_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000058866 |
| Target Classification | N/A |
The target: DGKG, gene name: DGKG, also named as DAGK3, DGK-GAMMA. This gene encodes an enzyme that is a member of the type I subfamily of diacylglycerol kinases, which are involved in lipid metabolism. These enzymes generate phosphatidic acid by catalyzing the phosphorylation of diacylglycerol, a fundamental lipid second messenger that activates numerous proteins, including protein kinase C isoforms, Ras guanyl nucleotide-releasing proteins and some transient receptor potential channels. Diacylglycerol kinase gamma has been implicated in cell cycle regulation and in the negative regulation of macrophage differentiation in leukemia cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
