Anti-DLG1/ DLGH1/ SAP-97 monoclonal antibody

Anti-DLG1/ DLGH1/ SAP-97 antibody for FACS & in-vivo assay

Target products collectionGo to DLG1/DLG1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2080-Ab-1/ GM-Tg-hg-MP2080-Ab-2Anti-Human DLG1 monoclonal antibodyHuman
GM-Tg-rg-MP2080-Ab-1/ GM-Tg-rg-MP2080-Ab-2Anti-Rat DLG1 monoclonal antibodyRat
GM-Tg-mg-MP2080-Ab-1/ GM-Tg-mg-MP2080-Ab-2Anti-Mouse DLG1 monoclonal antibodyMouse
GM-Tg-cynog-MP2080-Ab-1/ GM-Tg-cynog-MP2080-Ab-2Anti-Cynomolgus/ Rhesus macaque DLG1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2080-Ab-1/ GM-Tg-felg-MP2080-Ab-2Anti-Feline DLG1 monoclonal antibodyFeline
GM-Tg-cang-MP2080-Ab-1/ GM-Tg-cang-MP2080-Ab-2Anti-Canine DLG1 monoclonal antibodyCanine
GM-Tg-bovg-MP2080-Ab-1/ GM-Tg-bovg-MP2080-Ab-2Anti-Bovine DLG1 monoclonal antibodyBovine
GM-Tg-equg-MP2080-Ab-1/ GM-Tg-equg-MP2080-Ab-2Anti-Equine DLG1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2080-Ab-1/ GM-Tg-hg-MP2080-Ab-2; GM-Tg-rg-MP2080-Ab-1/ GM-Tg-rg-MP2080-Ab-2;
GM-Tg-mg-MP2080-Ab-1/ GM-Tg-mg-MP2080-Ab-2; GM-Tg-cynog-MP2080-Ab-1/ GM-Tg-cynog-MP2080-Ab-2;
GM-Tg-felg-MP2080-Ab-1/ GM-Tg-felg-MP2080-Ab-2; GM-Tg-cang-MP2080-Ab-1/ GM-Tg-cang-MP2080-Ab-2;
GM-Tg-bovg-MP2080-Ab-1/ GM-Tg-bovg-MP2080-Ab-2; GM-Tg-equg-MP2080-Ab-1/ GM-Tg-equg-MP2080-Ab-2
Products NameAnti-DLG1 monoclonal antibody
Formatmab
Target NameDLG1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-DLG1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species DLG1/ DLGH1/ SAP-97 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2080
    Target NameDLG1
    Gene ID1739,13383,25252,709572,488036,101084051,785291,100060094
    Gene Symbol and SynonymsB130052P05Rik,DLG1,DLGH1,E-dlg/SAP97,hdlg,mKIAA4187,SAP-97,SAP97
    Uniprot AccessionQ12959,Q62696
    Uniprot Entry NameDLG1_HUMAN,DLG1_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000075711
    Target ClassificationN/A

    The target: DLG1, gene name: DLG1, also named as DLGH1, SAP-97, SAP97, hdlg. This gene encodes a multi-domain scaffolding protein that is required for normal development. This protein may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. A multitude of transcript variants deriving from alternative splicing and the use of multiple alternate promoter have been observed, including some splice variants that may be specific to brain and other tissues. An upstream uORF may regulate translation at some splice variants of this gene. [provided by RefSeq, Sep 2018].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.