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Anti-DLG5/ LP-DLG/ P-DLG5 monoclonal antibody
Anti-DLG5/ LP-DLG/ P-DLG5 antibody for FACS & in-vivo assay
Go to DLG5/DLG5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2082-Ab-1/ GM-Tg-hg-MP2082-Ab-2 | Anti-Human DLG5 monoclonal antibody | Human |
| GM-Tg-rg-MP2082-Ab-1/ GM-Tg-rg-MP2082-Ab-2 | Anti-Rat DLG5 monoclonal antibody | Rat |
| GM-Tg-mg-MP2082-Ab-1/ GM-Tg-mg-MP2082-Ab-2 | Anti-Mouse DLG5 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2082-Ab-1/ GM-Tg-cynog-MP2082-Ab-2 | Anti-Cynomolgus/ Rhesus macaque DLG5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2082-Ab-1/ GM-Tg-felg-MP2082-Ab-2 | Anti-Feline DLG5 monoclonal antibody | Feline |
| GM-Tg-cang-MP2082-Ab-1/ GM-Tg-cang-MP2082-Ab-2 | Anti-Canine DLG5 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2082-Ab-1/ GM-Tg-bovg-MP2082-Ab-2 | Anti-Bovine DLG5 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2082-Ab-1/ GM-Tg-equg-MP2082-Ab-2 | Anti-Equine DLG5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2082-Ab-1/ GM-Tg-hg-MP2082-Ab-2; GM-Tg-rg-MP2082-Ab-1/ GM-Tg-rg-MP2082-Ab-2; GM-Tg-mg-MP2082-Ab-1/ GM-Tg-mg-MP2082-Ab-2; GM-Tg-cynog-MP2082-Ab-1/ GM-Tg-cynog-MP2082-Ab-2; GM-Tg-felg-MP2082-Ab-1/ GM-Tg-felg-MP2082-Ab-2; GM-Tg-cang-MP2082-Ab-1/ GM-Tg-cang-MP2082-Ab-2; GM-Tg-bovg-MP2082-Ab-1/ GM-Tg-bovg-MP2082-Ab-2; GM-Tg-equg-MP2082-Ab-1/ GM-Tg-equg-MP2082-Ab-2 |
| Products Name | Anti-DLG5 monoclonal antibody |
| Format | mab |
| Target Name | DLG5 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-DLG5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species DLG5/ LP-DLG/ P-DLG5 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP2082 |
| Target Name | DLG5 |
| Gene ID | 9231,71228,305645,703123,489061,101093803,535699,100072996 |
| Gene Symbol and Synonyms | 4933429D20Rik,DLG5,LP-DLG,mKIAA0583,P-DLG5,PDLG |
| Uniprot Accession | Q8TDM6 |
| Uniprot Entry Name | DLG5_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000151208 |
| Target Classification | N/A |
The target: DLG5, gene name: DLG5, also named as LP-DLG, P-DLG5, PDLG. This gene encodes a member of the family of discs large (DLG) homologs, a subset of the membrane-associated guanylate kinase (MAGUK) superfamily. The MAGUK proteins are composed of a catalytically inactive guanylate kinase domain, in addition to PDZ and SH3 domains, and are thought to function as scaffolding molecules at sites of cell-cell contact. The protein encoded by this gene localizes to the plasma membrane and cytoplasm, and interacts with components of adherens junctions and the cytoskeleton. It is proposed to function in the transmission of extracellular signals to the cytoskeleton and in the maintenance of epithelial cell structure. Alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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