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Anti-DAAF4/ DNAAF4/ CILD25 monoclonal antibody
Anti-DAAF4/ DNAAF4/ CILD25 antibody for FACS & in-vivo assay
Go to DNAAF4/DNAAF4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2084-Ab-1/ GM-Tg-hg-MP2084-Ab-2 | Anti-Human DNAAF4 monoclonal antibody | Human |
| GM-Tg-rg-MP2084-Ab-1/ GM-Tg-rg-MP2084-Ab-2 | Anti-Rat DNAAF4 monoclonal antibody | Rat |
| GM-Tg-mg-MP2084-Ab-1/ GM-Tg-mg-MP2084-Ab-2 | Anti-Mouse DNAAF4 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2084-Ab-1/ GM-Tg-cynog-MP2084-Ab-2 | Anti-Cynomolgus/ Rhesus macaque DNAAF4 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2084-Ab-1/ GM-Tg-felg-MP2084-Ab-2 | Anti-Feline DNAAF4 monoclonal antibody | Feline |
| GM-Tg-cang-MP2084-Ab-1/ GM-Tg-cang-MP2084-Ab-2 | Anti-Canine DNAAF4 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2084-Ab-1/ GM-Tg-bovg-MP2084-Ab-2 | Anti-Bovine DNAAF4 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2084-Ab-1/ GM-Tg-equg-MP2084-Ab-2 | Anti-Equine DNAAF4 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2084-Ab-1/ GM-Tg-hg-MP2084-Ab-2; GM-Tg-rg-MP2084-Ab-1/ GM-Tg-rg-MP2084-Ab-2; GM-Tg-mg-MP2084-Ab-1/ GM-Tg-mg-MP2084-Ab-2; GM-Tg-cynog-MP2084-Ab-1/ GM-Tg-cynog-MP2084-Ab-2; GM-Tg-felg-MP2084-Ab-1/ GM-Tg-felg-MP2084-Ab-2; GM-Tg-cang-MP2084-Ab-1/ GM-Tg-cang-MP2084-Ab-2; GM-Tg-bovg-MP2084-Ab-1/ GM-Tg-bovg-MP2084-Ab-2; GM-Tg-equg-MP2084-Ab-1/ GM-Tg-equg-MP2084-Ab-2 |
| Products Name | Anti-DNAAF4 monoclonal antibody |
| Format | mab |
| Target Name | DNAAF4 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-DNAAF4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species DAAF4/ DNAAF4/ CILD25 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP2084 |
| Target Name | DNAAF4 |
| Gene ID | 161582,67685,363096,100429795,487567,101085981,527393,100054782 |
| Gene Symbol and Synonyms | 1700010I24Rik,b2b811.1Clo,b2b811Clo,CILD25,DNAAF4,DYX1,DYX1C1,DYXC1,Edem2,EKN1,RD |
| Uniprot Accession | Q8WXU2,Q5VJS5 |
| Uniprot Entry Name | DAAF4_HUMAN,DAAF4_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000256061 |
| Target Classification | N/A |
The target: DNAAF4, gene name: DNAAF4, also named as CILD25, DYX1, DYX1C1, DYXC1, EKN1, RD. This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. An homologous protein in rat has been shown to function in neuronal migration in the developing neocortex. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream cell cycle progression 1 (CCPG1) gene. [provided by RefSeq, Mar 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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