Anti-DRP2/ DRP-2 monoclonal antibody

Anti-DRP2/ DRP-2 antibody for FACS & in-vivo assay

Target products collectionGo to DRP2/DRP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2088-Ab-1/ GM-Tg-hg-MP2088-Ab-2Anti-Human DRP2 monoclonal antibodyHuman
GM-Tg-rg-MP2088-Ab-1/ GM-Tg-rg-MP2088-Ab-2Anti-Rat DRP2 monoclonal antibodyRat
GM-Tg-mg-MP2088-Ab-1/ GM-Tg-mg-MP2088-Ab-2Anti-Mouse DRP2 monoclonal antibodyMouse
GM-Tg-cynog-MP2088-Ab-1/ GM-Tg-cynog-MP2088-Ab-2Anti-Cynomolgus/ Rhesus macaque DRP2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2088-Ab-1/ GM-Tg-felg-MP2088-Ab-2Anti-Feline DRP2 monoclonal antibodyFeline
GM-Tg-cang-MP2088-Ab-1/ GM-Tg-cang-MP2088-Ab-2Anti-Canine DRP2 monoclonal antibodyCanine
GM-Tg-bovg-MP2088-Ab-1/ GM-Tg-bovg-MP2088-Ab-2Anti-Bovine DRP2 monoclonal antibodyBovine
GM-Tg-equg-MP2088-Ab-1/ GM-Tg-equg-MP2088-Ab-2Anti-Equine DRP2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2088-Ab-1/ GM-Tg-hg-MP2088-Ab-2; GM-Tg-rg-MP2088-Ab-1/ GM-Tg-rg-MP2088-Ab-2;
GM-Tg-mg-MP2088-Ab-1/ GM-Tg-mg-MP2088-Ab-2; GM-Tg-cynog-MP2088-Ab-1/ GM-Tg-cynog-MP2088-Ab-2;
GM-Tg-felg-MP2088-Ab-1/ GM-Tg-felg-MP2088-Ab-2; GM-Tg-cang-MP2088-Ab-1/ GM-Tg-cang-MP2088-Ab-2;
GM-Tg-bovg-MP2088-Ab-1/ GM-Tg-bovg-MP2088-Ab-2; GM-Tg-equg-MP2088-Ab-1/ GM-Tg-equg-MP2088-Ab-2
Products NameAnti-DRP2 monoclonal antibody
Formatmab
Target NameDRP2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-DRP2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species DRP2/ DRP-2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2088
    Target NameDRP2
    Gene ID1821,13497,66027,702655,119868477,101087136,537422,100057542
    Gene Symbol and SynonymsDRP-2,DRP2
    Uniprot AccessionQ13474,Q9EPA0
    Uniprot Entry NameDRP2_HUMAN,DRP2_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000102385
    Target ClassificationN/A

    The target: DRP2, gene name: DRP2, also named as DRP-2. Members of the dystrophin family of proteins perform a critical role in the maintenance of membrane-associated complexes at points of intercellular contact in vertebrate cells. The protein encoded by this gene is predicted to resemble certain short C-terminal isoforms of dystrophin and dystrophin-related protein 1 (DRP1 or utrophin). DRP2 is expressed principally in the brain and spinal cord. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.