Anti-EF2/ EEF2/ EEF-2 monoclonal antibody

Anti-EF2/ EEF2/ EEF-2 antibody for FACS & in-vivo assay

Target products collectionGo to EEF2/EEF2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2092-Ab-1/ GM-Tg-hg-MP2092-Ab-2Anti-Human EEF2 monoclonal antibodyHuman
GM-Tg-rg-MP2092-Ab-1/ GM-Tg-rg-MP2092-Ab-2Anti-Rat EEF2 monoclonal antibodyRat
GM-Tg-mg-MP2092-Ab-1/ GM-Tg-mg-MP2092-Ab-2Anti-Mouse EEF2 monoclonal antibodyMouse
GM-Tg-cynog-MP2092-Ab-1/ GM-Tg-cynog-MP2092-Ab-2Anti-Cynomolgus/ Rhesus macaque EEF2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2092-Ab-1/ GM-Tg-felg-MP2092-Ab-2Anti-Feline EEF2 monoclonal antibodyFeline
GM-Tg-cang-MP2092-Ab-1/ GM-Tg-cang-MP2092-Ab-2Anti-Canine EEF2 monoclonal antibodyCanine
GM-Tg-bovg-MP2092-Ab-1/ GM-Tg-bovg-MP2092-Ab-2Anti-Bovine EEF2 monoclonal antibodyBovine
GM-Tg-equg-MP2092-Ab-1/ GM-Tg-equg-MP2092-Ab-2Anti-Equine EEF2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2092-Ab-1/ GM-Tg-hg-MP2092-Ab-2; GM-Tg-rg-MP2092-Ab-1/ GM-Tg-rg-MP2092-Ab-2;
GM-Tg-mg-MP2092-Ab-1/ GM-Tg-mg-MP2092-Ab-2; GM-Tg-cynog-MP2092-Ab-1/ GM-Tg-cynog-MP2092-Ab-2;
GM-Tg-felg-MP2092-Ab-1/ GM-Tg-felg-MP2092-Ab-2; GM-Tg-cang-MP2092-Ab-1/ GM-Tg-cang-MP2092-Ab-2;
GM-Tg-bovg-MP2092-Ab-1/ GM-Tg-bovg-MP2092-Ab-2; GM-Tg-equg-MP2092-Ab-1/ GM-Tg-equg-MP2092-Ab-2
Products NameAnti-EEF2 monoclonal antibody
Formatmab
Target NameEEF2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-EEF2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species EF2/ EEF2/ EEF-2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2092
    Target NameEEF2
    Gene ID1938,13629,29565,721806,476744,101089583,281138,100061437
    Gene Symbol and SynonymsEEF-2,EEF2,EF-2,EF2,SCA26
    Uniprot AccessionP13639,P05197,Q3SYU2
    Uniprot Entry NameEF2_HUMAN,EF2_RAT,EF2_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000167658
    Target ClassificationN/A

    The target: EEF2, gene name: EEF2, also named as EEF-2, EF-2, EF2, SCA26. This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.