Anti-EEPD1/ HSPC107 monoclonal antibody

Anti-EEPD1/ HSPC107 antibody for FACS & in-vivo assay

Target products collectionGo to EEPD1/EEPD1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2093-Ab-1/ GM-Tg-hg-MP2093-Ab-2Anti-Human EEPD1 monoclonal antibodyHuman
GM-Tg-rg-MP2093-Ab-1/ GM-Tg-rg-MP2093-Ab-2Anti-Rat EEPD1 monoclonal antibodyRat
GM-Tg-mg-MP2093-Ab-1/ GM-Tg-mg-MP2093-Ab-2Anti-Mouse EEPD1 monoclonal antibodyMouse
GM-Tg-cynog-MP2093-Ab-1/ GM-Tg-cynog-MP2093-Ab-2Anti-Cynomolgus/ Rhesus macaque EEPD1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2093-Ab-1/ GM-Tg-felg-MP2093-Ab-2Anti-Feline EEPD1 monoclonal antibodyFeline
GM-Tg-cang-MP2093-Ab-1/ GM-Tg-cang-MP2093-Ab-2Anti-Canine EEPD1 monoclonal antibodyCanine
GM-Tg-bovg-MP2093-Ab-1/ GM-Tg-bovg-MP2093-Ab-2Anti-Bovine EEPD1 monoclonal antibodyBovine
GM-Tg-equg-MP2093-Ab-1/ GM-Tg-equg-MP2093-Ab-2Anti-Equine EEPD1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2093-Ab-1/ GM-Tg-hg-MP2093-Ab-2; GM-Tg-rg-MP2093-Ab-1/ GM-Tg-rg-MP2093-Ab-2;
GM-Tg-mg-MP2093-Ab-1/ GM-Tg-mg-MP2093-Ab-2; GM-Tg-cynog-MP2093-Ab-1/ GM-Tg-cynog-MP2093-Ab-2;
GM-Tg-felg-MP2093-Ab-1/ GM-Tg-felg-MP2093-Ab-2; GM-Tg-cang-MP2093-Ab-1/ GM-Tg-cang-MP2093-Ab-2;
GM-Tg-bovg-MP2093-Ab-1/ GM-Tg-bovg-MP2093-Ab-2; GM-Tg-equg-MP2093-Ab-1/ GM-Tg-equg-MP2093-Ab-2
Products NameAnti-EEPD1 monoclonal antibody
Formatmab
Target NameEEPD1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-EEPD1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species EEPD1/ HSPC107 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2093
    Target NameEEPD1
    Gene ID80820,67484,315500,706642,482399,101100292,511767,100070517
    Gene Symbol and Synonyms2310005P05Rik,EEPD1,HSPC107,RGD1307401
    Uniprot AccessionQ7L9B9,Q5XI74,Q3MHJ7
    Uniprot Entry NameEEPD1_HUMAN,EEPD1_RAT,EEPD1_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000122547
    Target ClassificationN/A

    The target: EEPD1, gene name: EEPD1, also named as HSPC107. Predicted to enable DNA binding activity. Involved in positive regulation of cholesterol efflux. Is anchored component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.