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Anti-IF5/ EIF5/ EIF-5 monoclonal antibody
Anti-IF5/ EIF5/ EIF-5 antibody for FACS & in-vivo assay
Go to EIF5/EIF5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2101-Ab-1/ GM-Tg-hg-MP2101-Ab-2 | Anti-Human EIF5 monoclonal antibody | Human |
| GM-Tg-rg-MP2101-Ab-1/ GM-Tg-rg-MP2101-Ab-2 | Anti-Rat EIF5 monoclonal antibody | Rat |
| GM-Tg-mg-MP2101-Ab-1/ GM-Tg-mg-MP2101-Ab-2 | Anti-Mouse EIF5 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2101-Ab-1/ GM-Tg-cynog-MP2101-Ab-2 | Anti-Cynomolgus/ Rhesus macaque EIF5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2101-Ab-1/ GM-Tg-felg-MP2101-Ab-2 | Anti-Feline EIF5 monoclonal antibody | Feline |
| GM-Tg-cang-MP2101-Ab-1/ GM-Tg-cang-MP2101-Ab-2 | Anti-Canine EIF5 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2101-Ab-1/ GM-Tg-bovg-MP2101-Ab-2 | Anti-Bovine EIF5 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2101-Ab-1/ GM-Tg-equg-MP2101-Ab-2 | Anti-Equine EIF5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2101-Ab-1/ GM-Tg-hg-MP2101-Ab-2; GM-Tg-rg-MP2101-Ab-1/ GM-Tg-rg-MP2101-Ab-2; GM-Tg-mg-MP2101-Ab-1/ GM-Tg-mg-MP2101-Ab-2; GM-Tg-cynog-MP2101-Ab-1/ GM-Tg-cynog-MP2101-Ab-2; GM-Tg-felg-MP2101-Ab-1/ GM-Tg-felg-MP2101-Ab-2; GM-Tg-cang-MP2101-Ab-1/ GM-Tg-cang-MP2101-Ab-2; GM-Tg-bovg-MP2101-Ab-1/ GM-Tg-bovg-MP2101-Ab-2; GM-Tg-equg-MP2101-Ab-1/ GM-Tg-equg-MP2101-Ab-2 |
| Products Name | Anti-EIF5 monoclonal antibody |
| Format | mab |
| Target Name | EIF5 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-EIF5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species IF5/ EIF5/ EIF-5 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMAP000442 | Human EIF5 Adenovirus particle |
| ORF Viral Vector | pGMAP000442 | Human EIF5 Adenovirus plasmid |
| ORF Viral Vector | pGMLPm001418 | mouse Eif5 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001418 | mouse Eif5 Lentivirus particle |
Target information
| Target ID | GM-MP2101 |
| Target Name | EIF5 |
| Gene ID | 1983,217869,108348073,697538,480442,101097737,504752,100055152 |
| Gene Symbol and Synonyms | 2810011H21Rik,D12Ertd549e,EIF-5,EIF-5A,EIF5 |
| Uniprot Accession | P55010,Q07205 |
| Uniprot Entry Name | IF5_HUMAN,IF5_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000100664 |
| Target Classification | N/A |
The target: EIF5, gene name: EIF5, also named as EIF-5, EIF-5A. Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).[supplied by OMIM, May 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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