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Anti-ENOB/ ENO3/ GSD13 monoclonal antibody
Anti-ENOB/ ENO3/ GSD13 antibody for FACS & in-vivo assay
Go to ENO3/ENO3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2103-Ab-1/ GM-Tg-hg-MP2103-Ab-2 | Anti-Human ENO3 monoclonal antibody | Human |
| GM-Tg-rg-MP2103-Ab-1/ GM-Tg-rg-MP2103-Ab-2 | Anti-Rat ENO3 monoclonal antibody | Rat |
| GM-Tg-mg-MP2103-Ab-1/ GM-Tg-mg-MP2103-Ab-2 | Anti-Mouse ENO3 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2103-Ab-1/ GM-Tg-cynog-MP2103-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ENO3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2103-Ab-1/ GM-Tg-felg-MP2103-Ab-2 | Anti-Feline ENO3 monoclonal antibody | Feline |
| GM-Tg-cang-MP2103-Ab-1/ GM-Tg-cang-MP2103-Ab-2 | Anti-Canine ENO3 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2103-Ab-1/ GM-Tg-bovg-MP2103-Ab-2 | Anti-Bovine ENO3 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2103-Ab-1/ GM-Tg-equg-MP2103-Ab-2 | Anti-Equine ENO3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2103-Ab-1/ GM-Tg-hg-MP2103-Ab-2; GM-Tg-rg-MP2103-Ab-1/ GM-Tg-rg-MP2103-Ab-2; GM-Tg-mg-MP2103-Ab-1/ GM-Tg-mg-MP2103-Ab-2; GM-Tg-cynog-MP2103-Ab-1/ GM-Tg-cynog-MP2103-Ab-2; GM-Tg-felg-MP2103-Ab-1/ GM-Tg-felg-MP2103-Ab-2; GM-Tg-cang-MP2103-Ab-1/ GM-Tg-cang-MP2103-Ab-2; GM-Tg-bovg-MP2103-Ab-1/ GM-Tg-bovg-MP2103-Ab-2; GM-Tg-equg-MP2103-Ab-1/ GM-Tg-equg-MP2103-Ab-2 |
| Products Name | Anti-ENO3 monoclonal antibody |
| Format | mab |
| Target Name | ENO3 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-ENO3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species ENOB/ ENO3/ GSD13 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP003927 | human ENO3 Lentivirus plasmid |
| ORF Viral Vector | vGMLP003927 | human ENO3 Lentivirus particle |
| ORF Viral Vector | pGMLPm002190 | mouse Eno3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002190 | mouse Eno3 Lentivirus particle |
Target information
| Target ID | GM-MP2103 |
| Target Name | ENO3 |
| Gene ID | 2027,13808,25438,721589,479469,101091162,540303,100061187 |
| Gene Symbol and Synonyms | BBE,Eno-3,ENO3,GSD13,MSE |
| Uniprot Accession | P13929,P15429,Q3ZC09 |
| Uniprot Entry Name | ENOB_HUMAN,ENOB_RAT,ENOB_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000108515 |
| Target Classification | N/A |
The target: ENO3, gene name: ENO3, also named as GSD13, MSE. This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme is found in skeletal muscle cells in the adult where it may play a role in muscle development and regeneration. A switch from alpha enolase to beta enolase occurs in muscle tissue during development in rodents. Mutations in this gene have be associated glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jul 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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