Anti-EPN1 monoclonal antibody

Anti-EPN1 antibody for FACS & in-vivo assay

Target products collectionGo to EPN1/EPN1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2110-Ab-1/ GM-Tg-hg-MP2110-Ab-2Anti-Human EPN1 monoclonal antibodyHuman
GM-Tg-rg-MP2110-Ab-1/ GM-Tg-rg-MP2110-Ab-2Anti-Rat EPN1 monoclonal antibodyRat
GM-Tg-mg-MP2110-Ab-1/ GM-Tg-mg-MP2110-Ab-2Anti-Mouse EPN1 monoclonal antibodyMouse
GM-Tg-cynog-MP2110-Ab-1/ GM-Tg-cynog-MP2110-Ab-2Anti-Cynomolgus/ Rhesus macaque EPN1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2110-Ab-1/ GM-Tg-felg-MP2110-Ab-2Anti-Feline EPN1 monoclonal antibodyFeline
GM-Tg-cang-MP2110-Ab-1/ GM-Tg-cang-MP2110-Ab-2Anti-Canine EPN1 monoclonal antibodyCanine
GM-Tg-bovg-MP2110-Ab-1/ GM-Tg-bovg-MP2110-Ab-2Anti-Bovine EPN1 monoclonal antibodyBovine
GM-Tg-equg-MP2110-Ab-1/ GM-Tg-equg-MP2110-Ab-2Anti-Equine EPN1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2110-Ab-1/ GM-Tg-hg-MP2110-Ab-2; GM-Tg-rg-MP2110-Ab-1/ GM-Tg-rg-MP2110-Ab-2;
GM-Tg-mg-MP2110-Ab-1/ GM-Tg-mg-MP2110-Ab-2; GM-Tg-cynog-MP2110-Ab-1/ GM-Tg-cynog-MP2110-Ab-2;
GM-Tg-felg-MP2110-Ab-1/ GM-Tg-felg-MP2110-Ab-2; GM-Tg-cang-MP2110-Ab-1/ GM-Tg-cang-MP2110-Ab-2;
GM-Tg-bovg-MP2110-Ab-1/ GM-Tg-bovg-MP2110-Ab-2; GM-Tg-equg-MP2110-Ab-1/ GM-Tg-equg-MP2110-Ab-2
Products NameAnti-EPN1 monoclonal antibody
Formatmab
Target NameEPN1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-EPN1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species EPN1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2110
    Target NameEPN1
    Gene ID29924,13854,117277,702956,608964,101082281,508199,100050807
    Gene Symbol and SynonymsEPN1,Ibp1
    Uniprot AccessionQ9Y6I3,O88339
    Uniprot Entry NameEPN1_HUMAN,EPN1_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000063245
    Target ClassificationN/A

    The target: EPN1, gene name: EPN1, also named as . This gene encodes a member of the epsin protein family. The encoded protein binds clathrin and is involved in the endocytosis of clathrin-coated vesicles. Loss of function of this gene is associated with reduced tumor growth and progression in certain cancer types. [provided by RefSeq, Mar 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.