Anti-EXOC1/ BM-102/ SEC3 monoclonal antibody

Anti-EXOC1/ BM-102/ SEC3 antibody for FACS & in-vivo assay

Target products collectionGo to EXOC1/EXOC1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2113-Ab-1/ GM-Tg-hg-MP2113-Ab-2Anti-Human EXOC1 monoclonal antibodyHuman
GM-Tg-rg-MP2113-Ab-1/ GM-Tg-rg-MP2113-Ab-2Anti-Rat EXOC1 monoclonal antibodyRat
GM-Tg-mg-MP2113-Ab-1/ GM-Tg-mg-MP2113-Ab-2Anti-Mouse EXOC1 monoclonal antibodyMouse
GM-Tg-cynog-MP2113-Ab-1/ GM-Tg-cynog-MP2113-Ab-2Anti-Cynomolgus/ Rhesus macaque EXOC1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2113-Ab-1/ GM-Tg-felg-MP2113-Ab-2Anti-Feline EXOC1 monoclonal antibodyFeline
GM-Tg-cang-MP2113-Ab-1/ GM-Tg-cang-MP2113-Ab-2Anti-Canine EXOC1 monoclonal antibodyCanine
GM-Tg-bovg-MP2113-Ab-1/ GM-Tg-bovg-MP2113-Ab-2Anti-Bovine EXOC1 monoclonal antibodyBovine
GM-Tg-equg-MP2113-Ab-1/ GM-Tg-equg-MP2113-Ab-2Anti-Equine EXOC1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2113-Ab-1/ GM-Tg-hg-MP2113-Ab-2; GM-Tg-rg-MP2113-Ab-1/ GM-Tg-rg-MP2113-Ab-2;
GM-Tg-mg-MP2113-Ab-1/ GM-Tg-mg-MP2113-Ab-2; GM-Tg-cynog-MP2113-Ab-1/ GM-Tg-cynog-MP2113-Ab-2;
GM-Tg-felg-MP2113-Ab-1/ GM-Tg-felg-MP2113-Ab-2; GM-Tg-cang-MP2113-Ab-1/ GM-Tg-cang-MP2113-Ab-2;
GM-Tg-bovg-MP2113-Ab-1/ GM-Tg-bovg-MP2113-Ab-2; GM-Tg-equg-MP2113-Ab-1/ GM-Tg-equg-MP2113-Ab-2
Products NameAnti-EXOC1 monoclonal antibody
Formatmab
Target NameEXOC1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-EXOC1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species EXOC1/ BM-102/ SEC3 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2113
    Target NameEXOC1
    Gene ID55763,69940,305287,695664,475149,101088235,504440,100059087
    Gene Symbol and Synonyms2810407P21Rik,A730011E05Rik,BM-102,EXOC1,SEC3,SEC3L1,SEC3P
    Uniprot AccessionQ9NV70
    Uniprot Entry NameEXOC1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000090989
    Target ClassificationN/A

    The target: EXOC1, gene name: EXOC1, also named as BM-102, SEC3, SEC3L1, SEC3P. The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.