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Anti-EXOC7/ 2-5-3p/ BLOM4 monoclonal antibody
Anti-EXOC7/ 2-5-3p/ BLOM4 antibody for FACS & in-vivo assay
Go to EXOC7/EXOC7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2114-Ab-1/ GM-Tg-hg-MP2114-Ab-2 | Anti-Human EXOC7 monoclonal antibody | Human |
| GM-Tg-rg-MP2114-Ab-1/ GM-Tg-rg-MP2114-Ab-2 | Anti-Rat EXOC7 monoclonal antibody | Rat |
| GM-Tg-mg-MP2114-Ab-1/ GM-Tg-mg-MP2114-Ab-2 | Anti-Mouse EXOC7 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2114-Ab-1/ GM-Tg-cynog-MP2114-Ab-2 | Anti-Cynomolgus/ Rhesus macaque EXOC7 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2114-Ab-1/ GM-Tg-felg-MP2114-Ab-2 | Anti-Feline EXOC7 monoclonal antibody | Feline |
| GM-Tg-cang-MP2114-Ab-1/ GM-Tg-cang-MP2114-Ab-2 | Anti-Canine EXOC7 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2114-Ab-1/ GM-Tg-bovg-MP2114-Ab-2 | Anti-Bovine EXOC7 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2114-Ab-1/ GM-Tg-equg-MP2114-Ab-2 | Anti-Equine EXOC7 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2114-Ab-1/ GM-Tg-hg-MP2114-Ab-2; GM-Tg-rg-MP2114-Ab-1/ GM-Tg-rg-MP2114-Ab-2; GM-Tg-mg-MP2114-Ab-1/ GM-Tg-mg-MP2114-Ab-2; GM-Tg-cynog-MP2114-Ab-1/ GM-Tg-cynog-MP2114-Ab-2; GM-Tg-felg-MP2114-Ab-1/ GM-Tg-felg-MP2114-Ab-2; GM-Tg-cang-MP2114-Ab-1/ GM-Tg-cang-MP2114-Ab-2; GM-Tg-bovg-MP2114-Ab-1/ GM-Tg-bovg-MP2114-Ab-2; GM-Tg-equg-MP2114-Ab-1/ GM-Tg-equg-MP2114-Ab-2 |
| Products Name | Anti-EXOC7 monoclonal antibody |
| Format | mab |
| Target Name | EXOC7 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-EXOC7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species EXOC7/ 2-5-3p/ BLOM4 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLPm003897 | mouse Exoc7 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm003898 | mouse Exoc7 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003897 | mouse Exoc7 Lentivirus particle |
| ORF Viral Vector | vGMLPm003898 | mouse Exoc7 Lentivirus particle |
Target information
| Target ID | GM-MP2114 |
| Target Name | EXOC7 |
| Gene ID | 23265,53413,64632,705801,100682715,101083815,505568,100059108 |
| Gene Symbol and Synonyms | 2-5-3p,BLOM4,EX070,EXO70,Exo70p,EXOC1,EXOC7,NEDSEBA,sec70,YJL085W |
| Uniprot Accession | Q9UPT5,O54922 |
| Uniprot Entry Name | EXOC7_HUMAN,EXOC7_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000182473 |
| Target Classification | N/A |
The target: EXOC7, gene name: EXOC7, also named as 2-5-3p, BLOM4, EX070, EXO70, EXOC1, Exo70p, YJL085W. The protein encoded by this gene is a component of the exocyst complex. The exocyst complex plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. The encoded protein is required for assembly of the exocyst complex and docking of the complex to the plasma membrane. The encoded protein may also play a role in pre-mRNA splicing through interactions with pre-mRNA-processing factor 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Nov 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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