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Anti-FANCG/ FAG/ XRCC9 monoclonal antibody
Anti-FANCG/ FAG/ XRCC9 antibody for FACS & in-vivo assay
Go to FANCG/FANCG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2120-Ab-1/ GM-Tg-hg-MP2120-Ab-2 | Anti-Human FANCG monoclonal antibody | Human |
| GM-Tg-rg-MP2120-Ab-1/ GM-Tg-rg-MP2120-Ab-2 | Anti-Rat FANCG monoclonal antibody | Rat |
| GM-Tg-mg-MP2120-Ab-1/ GM-Tg-mg-MP2120-Ab-2 | Anti-Mouse FANCG monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2120-Ab-1/ GM-Tg-cynog-MP2120-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FANCG monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2120-Ab-1/ GM-Tg-felg-MP2120-Ab-2 | Anti-Feline FANCG monoclonal antibody | Feline |
| GM-Tg-cang-MP2120-Ab-1/ GM-Tg-cang-MP2120-Ab-2 | Anti-Canine FANCG monoclonal antibody | Canine |
| GM-Tg-bovg-MP2120-Ab-1/ GM-Tg-bovg-MP2120-Ab-2 | Anti-Bovine FANCG monoclonal antibody | Bovine |
| GM-Tg-equg-MP2120-Ab-1/ GM-Tg-equg-MP2120-Ab-2 | Anti-Equine FANCG monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2120-Ab-1/ GM-Tg-hg-MP2120-Ab-2; GM-Tg-rg-MP2120-Ab-1/ GM-Tg-rg-MP2120-Ab-2; GM-Tg-mg-MP2120-Ab-1/ GM-Tg-mg-MP2120-Ab-2; GM-Tg-cynog-MP2120-Ab-1/ GM-Tg-cynog-MP2120-Ab-2; GM-Tg-felg-MP2120-Ab-1/ GM-Tg-felg-MP2120-Ab-2; GM-Tg-cang-MP2120-Ab-1/ GM-Tg-cang-MP2120-Ab-2; GM-Tg-bovg-MP2120-Ab-1/ GM-Tg-bovg-MP2120-Ab-2; GM-Tg-equg-MP2120-Ab-1/ GM-Tg-equg-MP2120-Ab-2 |
| Products Name | Anti-FANCG monoclonal antibody |
| Format | mab |
| Target Name | FANCG |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-FANCG benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species FANCG/ FAG/ XRCC9 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP2120 |
| Target Name | FANCG |
| Gene ID | 2189,60534,691105,698837,611887,101091661,615352,100068211 |
| Gene Symbol and Synonyms | FAG,FANCG,XRCC9 |
| Uniprot Accession | O15287 |
| Uniprot Entry Name | FANCG_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000221829 |
| Target Classification | N/A |
The target: FANCG, gene name: FANCG, also named as FAG, XRCC9. The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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