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Anti-FMN2 monoclonal antibody
Anti-FMN2 antibody for FACS & in-vivo assay
Go to FMN2/FMN2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2130-Ab-1/ GM-Tg-hg-MP2130-Ab-2 | Anti-Human FMN2 monoclonal antibody | Human |
| GM-Tg-rg-MP2130-Ab-1/ GM-Tg-rg-MP2130-Ab-2 | Anti-Rat FMN2 monoclonal antibody | Rat |
| GM-Tg-mg-MP2130-Ab-1/ GM-Tg-mg-MP2130-Ab-2 | Anti-Mouse FMN2 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2130-Ab-1/ GM-Tg-cynog-MP2130-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FMN2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2130-Ab-1/ GM-Tg-felg-MP2130-Ab-2 | Anti-Feline FMN2 monoclonal antibody | Feline |
| GM-Tg-cang-MP2130-Ab-1/ GM-Tg-cang-MP2130-Ab-2 | Anti-Canine FMN2 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2130-Ab-1/ GM-Tg-bovg-MP2130-Ab-2 | Anti-Bovine FMN2 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2130-Ab-1/ GM-Tg-equg-MP2130-Ab-2 | Anti-Equine FMN2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2130-Ab-1/ GM-Tg-hg-MP2130-Ab-2; GM-Tg-rg-MP2130-Ab-1/ GM-Tg-rg-MP2130-Ab-2; GM-Tg-mg-MP2130-Ab-1/ GM-Tg-mg-MP2130-Ab-2; GM-Tg-cynog-MP2130-Ab-1/ GM-Tg-cynog-MP2130-Ab-2; GM-Tg-felg-MP2130-Ab-1/ GM-Tg-felg-MP2130-Ab-2; GM-Tg-cang-MP2130-Ab-1/ GM-Tg-cang-MP2130-Ab-2; GM-Tg-bovg-MP2130-Ab-1/ GM-Tg-bovg-MP2130-Ab-2; GM-Tg-equg-MP2130-Ab-1/ GM-Tg-equg-MP2130-Ab-2 |
| Products Name | Anti-FMN2 monoclonal antibody |
| Format | mab |
| Target Name | FMN2 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-FMN2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species FMN2 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP2130 |
| Target Name | FMN2 |
| Gene ID | 56776,54418,100360457,708376,490366,101097037,100060203 |
| Gene Symbol and Synonyms | AABR07021812.1,FMN2 |
| Uniprot Accession | Q9NZ56 |
| Uniprot Entry Name | FMN2_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000155816 |
| Target Classification | N/A |
The target: FMN2, gene name: FMN2, also named as . This gene is a member of the formin homology protein family. The encoded protein is thought to have essential roles in organization of the actin cytoskeleton and in cell polarity. This protein mediates the formation of an actin mesh that positions the spindle during oogenesis and also regulates the formation of actin filaments in the nucleus. This protein also forms a perinuclear actin/focal-adhesion system that regulates the shape and position of the nucleus during cell migration. Mutations in this gene have been associated with infertility and also with an autosomal recessive form of intellectual disability (MRT47). Alternatively spliced transcript variants have been identified. [provided by RefSeq, Jul 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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