Anti-FYB1/ ADAP/ FYB monoclonal antibody

Anti-FYB1/ ADAP/ FYB antibody for FACS & in-vivo assay

Target products collectionGo to FYB1/FYB1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2134-Ab-1/ GM-Tg-hg-MP2134-Ab-2Anti-Human FYB1 monoclonal antibodyHuman
GM-Tg-rg-MP2134-Ab-1/ GM-Tg-rg-MP2134-Ab-2Anti-Rat FYB1 monoclonal antibodyRat
GM-Tg-mg-MP2134-Ab-1/ GM-Tg-mg-MP2134-Ab-2Anti-Mouse FYB1 monoclonal antibodyMouse
GM-Tg-cynog-MP2134-Ab-1/ GM-Tg-cynog-MP2134-Ab-2Anti-Cynomolgus/ Rhesus macaque FYB1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2134-Ab-1/ GM-Tg-felg-MP2134-Ab-2Anti-Feline FYB1 monoclonal antibodyFeline
GM-Tg-cang-MP2134-Ab-1/ GM-Tg-cang-MP2134-Ab-2Anti-Canine FYB1 monoclonal antibodyCanine
GM-Tg-bovg-MP2134-Ab-1/ GM-Tg-bovg-MP2134-Ab-2Anti-Bovine FYB1 monoclonal antibodyBovine
GM-Tg-equg-MP2134-Ab-1/ GM-Tg-equg-MP2134-Ab-2Anti-Equine FYB1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2134-Ab-1/ GM-Tg-hg-MP2134-Ab-2; GM-Tg-rg-MP2134-Ab-1/ GM-Tg-rg-MP2134-Ab-2;
GM-Tg-mg-MP2134-Ab-1/ GM-Tg-mg-MP2134-Ab-2; GM-Tg-cynog-MP2134-Ab-1/ GM-Tg-cynog-MP2134-Ab-2;
GM-Tg-felg-MP2134-Ab-1/ GM-Tg-felg-MP2134-Ab-2; GM-Tg-cang-MP2134-Ab-1/ GM-Tg-cang-MP2134-Ab-2;
GM-Tg-bovg-MP2134-Ab-1/ GM-Tg-bovg-MP2134-Ab-2; GM-Tg-equg-MP2134-Ab-1/ GM-Tg-equg-MP2134-Ab-2
Products NameAnti-FYB1 monoclonal antibody
Formatmab
Target NameFYB1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-FYB1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species FYB1/ ADAP/ FYB VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2134
    Target NameFYB1
    Gene ID2533,23880,499537,693951,479355,101095954,535347,100066754
    Gene Symbol and SynonymsADAP,B630013F22Rik,FYB,FYB-120/130,FYB1,p120/130,p120/p130,PRO0823,RGD1563421,SLAP-130,SLAP130,THC3
    Uniprot AccessionO15117,D3ZIE4
    Uniprot Entry NameFYB1_HUMAN,FYB1_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000082074
    Target ClassificationN/A

    The target: FYB1, gene name: FYB1, also named as ADAP, FYB, PRO0823, SLAP-130, SLAP130, THC3. The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interleukin-2. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.