Anti-GAS7 monoclonal antibody

Anti-GAS7 antibody for FACS & in-vivo assay

Target products collectionGo to GAS7/GAS7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2137-Ab-1/ GM-Tg-hg-MP2137-Ab-2Anti-Human GAS7 monoclonal antibodyHuman
GM-Tg-rg-MP2137-Ab-1/ GM-Tg-rg-MP2137-Ab-2Anti-Rat GAS7 monoclonal antibodyRat
GM-Tg-mg-MP2137-Ab-1/ GM-Tg-mg-MP2137-Ab-2Anti-Mouse GAS7 monoclonal antibodyMouse
GM-Tg-cynog-MP2137-Ab-1/ GM-Tg-cynog-MP2137-Ab-2Anti-Cynomolgus/ Rhesus macaque GAS7 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2137-Ab-1/ GM-Tg-felg-MP2137-Ab-2Anti-Feline GAS7 monoclonal antibodyFeline
GM-Tg-cang-MP2137-Ab-1/ GM-Tg-cang-MP2137-Ab-2Anti-Canine GAS7 monoclonal antibodyCanine
GM-Tg-bovg-MP2137-Ab-1/ GM-Tg-bovg-MP2137-Ab-2Anti-Bovine GAS7 monoclonal antibodyBovine
GM-Tg-equg-MP2137-Ab-1/ GM-Tg-equg-MP2137-Ab-2Anti-Equine GAS7 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2137-Ab-1/ GM-Tg-hg-MP2137-Ab-2; GM-Tg-rg-MP2137-Ab-1/ GM-Tg-rg-MP2137-Ab-2;
GM-Tg-mg-MP2137-Ab-1/ GM-Tg-mg-MP2137-Ab-2; GM-Tg-cynog-MP2137-Ab-1/ GM-Tg-cynog-MP2137-Ab-2;
GM-Tg-felg-MP2137-Ab-1/ GM-Tg-felg-MP2137-Ab-2; GM-Tg-cang-MP2137-Ab-1/ GM-Tg-cang-MP2137-Ab-2;
GM-Tg-bovg-MP2137-Ab-1/ GM-Tg-bovg-MP2137-Ab-2; GM-Tg-equg-MP2137-Ab-1/ GM-Tg-equg-MP2137-Ab-2
Products NameAnti-GAS7 monoclonal antibody
Formatmab
Target NameGAS7
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GAS7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GAS7 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2137
    Target NameGAS7
    Gene ID8522,14457,85246,717827,608189,101084661,614517,100073080
    Gene Symbol and SynonymsB230343A10Rik,GAS7,Gas7-cb
    Uniprot AccessionO60861,O55148
    Uniprot Entry NameGAS7_HUMAN,GAS7_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseCancer
    Gene EnsemblENSG00000007237
    Target ClassificationTumor-associated antigen (TAA)

    The target: GAS7, gene name: GAS7, also named as . Growth arrest-specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development. Several transcript variants encoding proteins which vary in the N-terminus have been described. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.