Anti-GBG2/ GNG2 monoclonal antibody

Anti-GBG2/ GNG2 antibody for FACS & in-vivo assay

Target products collectionGo to GNG2/GNG2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2148-Ab-1/ GM-Tg-hg-MP2148-Ab-2Anti-Human GNG2 monoclonal antibodyHuman
GM-Tg-rg-MP2148-Ab-1/ GM-Tg-rg-MP2148-Ab-2Anti-Rat GNG2 monoclonal antibodyRat
GM-Tg-mg-MP2148-Ab-1/ GM-Tg-mg-MP2148-Ab-2Anti-Mouse GNG2 monoclonal antibodyMouse
GM-Tg-cynog-MP2148-Ab-1/ GM-Tg-cynog-MP2148-Ab-2Anti-Cynomolgus/ Rhesus macaque GNG2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2148-Ab-1/ GM-Tg-felg-MP2148-Ab-2Anti-Feline GNG2 monoclonal antibodyFeline
GM-Tg-cang-MP2148-Ab-1/ GM-Tg-cang-MP2148-Ab-2Anti-Canine GNG2 monoclonal antibodyCanine
GM-Tg-bovg-MP2148-Ab-1/ GM-Tg-bovg-MP2148-Ab-2Anti-Bovine GNG2 monoclonal antibodyBovine
GM-Tg-equg-MP2148-Ab-1/ GM-Tg-equg-MP2148-Ab-2Anti-Equine GNG2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2148-Ab-1/ GM-Tg-hg-MP2148-Ab-2; GM-Tg-rg-MP2148-Ab-1/ GM-Tg-rg-MP2148-Ab-2;
GM-Tg-mg-MP2148-Ab-1/ GM-Tg-mg-MP2148-Ab-2; GM-Tg-cynog-MP2148-Ab-1/ GM-Tg-cynog-MP2148-Ab-2;
GM-Tg-felg-MP2148-Ab-1/ GM-Tg-felg-MP2148-Ab-2; GM-Tg-cang-MP2148-Ab-1/ GM-Tg-cang-MP2148-Ab-2;
GM-Tg-bovg-MP2148-Ab-1/ GM-Tg-bovg-MP2148-Ab-2; GM-Tg-equg-MP2148-Ab-1/ GM-Tg-equg-MP2148-Ab-2
Products NameAnti-GNG2 monoclonal antibody
Formatmab
Target NameGNG2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GNG2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GBG2/ GNG2 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP000165human GNG2 Lentivirus particle
    ORF Viral VectorpGMLP000165human GNG2 Lentivirus plasmid
    ORF Viral VectorpGMLPm001114mouse Gng2 Lentivirus plasmid
    ORF Viral VectorvGMLPm001114mouse Gng2 Lentivirus particle


    Target information

    Target IDGM-MP2148
    Target NameGNG2
    Gene ID54331,14702,80850,710000,610817,101097491,281203,100630067
    Gene Symbol and SynonymsGNG2,HG3F1
    Uniprot AccessionP59768,P63212
    Uniprot Entry NameGBG2_HUMAN,GBG2_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000186469
    Target ClassificationN/A

    The target: GNG2, gene name: GNG2, also named as . This gene encodes one of the gamma subunits of a guanine nucleotide-binding protein. Such proteins are involved in signaling mechanisms across membranes. Various subunits forms heterodimers which then interact with the different signal molecules. [provided by RefSeq, Aug 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.