Anti-HCFC2/ HCF-2/ HCF2 monoclonal antibody

Anti-HCFC2/ HCF-2/ HCF2 antibody for FACS & in-vivo assay

Target products collectionGo to HCFC2/HCFC2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2156-Ab-1/ GM-Tg-hg-MP2156-Ab-2Anti-Human HCFC2 monoclonal antibodyHuman
GM-Tg-rg-MP2156-Ab-1/ GM-Tg-rg-MP2156-Ab-2Anti-Rat HCFC2 monoclonal antibodyRat
GM-Tg-mg-MP2156-Ab-1/ GM-Tg-mg-MP2156-Ab-2Anti-Mouse HCFC2 monoclonal antibodyMouse
GM-Tg-cynog-MP2156-Ab-1/ GM-Tg-cynog-MP2156-Ab-2Anti-Cynomolgus/ Rhesus macaque HCFC2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2156-Ab-1/ GM-Tg-felg-MP2156-Ab-2Anti-Feline HCFC2 monoclonal antibodyFeline
GM-Tg-cang-MP2156-Ab-1/ GM-Tg-cang-MP2156-Ab-2Anti-Canine HCFC2 monoclonal antibodyCanine
GM-Tg-bovg-MP2156-Ab-1/ GM-Tg-bovg-MP2156-Ab-2Anti-Bovine HCFC2 monoclonal antibodyBovine
GM-Tg-equg-MP2156-Ab-1/ GM-Tg-equg-MP2156-Ab-2Anti-Equine HCFC2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2156-Ab-1/ GM-Tg-hg-MP2156-Ab-2; GM-Tg-rg-MP2156-Ab-1/ GM-Tg-rg-MP2156-Ab-2;
GM-Tg-mg-MP2156-Ab-1/ GM-Tg-mg-MP2156-Ab-2; GM-Tg-cynog-MP2156-Ab-1/ GM-Tg-cynog-MP2156-Ab-2;
GM-Tg-felg-MP2156-Ab-1/ GM-Tg-felg-MP2156-Ab-2; GM-Tg-cang-MP2156-Ab-1/ GM-Tg-cang-MP2156-Ab-2;
GM-Tg-bovg-MP2156-Ab-1/ GM-Tg-bovg-MP2156-Ab-2; GM-Tg-equg-MP2156-Ab-1/ GM-Tg-equg-MP2156-Ab-2
Products NameAnti-HCFC2 monoclonal antibody
Formatmab
Target NameHCFC2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-HCFC2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species HCFC2/ HCF-2/ HCF2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2156
    Target NameHCFC2
    Gene ID29915,67933,314704,700316,475449,101084553,505341,100067735
    Gene Symbol and Synonyms1700129L13Rik,fkls,HCF-2,HCF2,HCFC2
    Uniprot AccessionQ9Y5Z7,Q5RKG2
    Uniprot Entry NameHCFC2_HUMAN,HCFC2_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000111727
    Target ClassificationN/A

    The target: HCFC2, gene name: HCFC2, also named as HCF-2, HCF2. This gene encodes one of two proteins which interact with VP16, a herpes simplex virus protein that initiates virus infection. Both the encoded protein and the original Herpes host cell factor interact with VP16 through a beta-propeller domain. The original Herpes host cell factor, however, is effective at initiating viral infection while the encoded protein is not. Transcripts of varying length due to alternative polyadenylation signals have been described. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.