Anti-KANL2/ KANSL2/ C12orf41 monoclonal antibody

Anti-KANL2/ KANSL2/ C12orf41 antibody for FACS & in-vivo assay

Target products collectionGo to KANSL2/KANSL2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2171-Ab-1/ GM-Tg-hg-MP2171-Ab-2Anti-Human KANSL2 monoclonal antibodyHuman
GM-Tg-rg-MP2171-Ab-1/ GM-Tg-rg-MP2171-Ab-2Anti-Rat KANSL2 monoclonal antibodyRat
GM-Tg-mg-MP2171-Ab-1/ GM-Tg-mg-MP2171-Ab-2Anti-Mouse KANSL2 monoclonal antibodyMouse
GM-Tg-cynog-MP2171-Ab-1/ GM-Tg-cynog-MP2171-Ab-2Anti-Cynomolgus/ Rhesus macaque KANSL2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2171-Ab-1/ GM-Tg-felg-MP2171-Ab-2Anti-Feline KANSL2 monoclonal antibodyFeline
GM-Tg-cang-MP2171-Ab-1/ GM-Tg-cang-MP2171-Ab-2Anti-Canine KANSL2 monoclonal antibodyCanine
GM-Tg-bovg-MP2171-Ab-1/ GM-Tg-bovg-MP2171-Ab-2Anti-Bovine KANSL2 monoclonal antibodyBovine
GM-Tg-equg-MP2171-Ab-1/ GM-Tg-equg-MP2171-Ab-2Anti-Equine KANSL2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2171-Ab-1/ GM-Tg-hg-MP2171-Ab-2; GM-Tg-rg-MP2171-Ab-1/ GM-Tg-rg-MP2171-Ab-2;
GM-Tg-mg-MP2171-Ab-1/ GM-Tg-mg-MP2171-Ab-2; GM-Tg-cynog-MP2171-Ab-1/ GM-Tg-cynog-MP2171-Ab-2;
GM-Tg-felg-MP2171-Ab-1/ GM-Tg-felg-MP2171-Ab-2; GM-Tg-cang-MP2171-Ab-1/ GM-Tg-cang-MP2171-Ab-2;
GM-Tg-bovg-MP2171-Ab-1/ GM-Tg-bovg-MP2171-Ab-2; GM-Tg-equg-MP2171-Ab-1/ GM-Tg-equg-MP2171-Ab-2
Products NameAnti-KANSL2 monoclonal antibody
Formatmab
Target NameKANSL2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-KANSL2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species KANL2/ KANSL2/ C12orf41 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2171
    Target NameKANSL2
    Gene ID54934,69612,300206,709517,609028,101090449,540194,100058626
    Gene Symbol and Synonyms2310037I24Rik,B930009D17,C12orf41,C5H12orf41,C5HANSL2,KANSL2,NSL2,RGD1303127
    Uniprot AccessionQ9H9L4,Q6AY70,Q2NL14
    Uniprot Entry NameKANL2_HUMAN,KANL2_RAT,KANL2_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000139620
    Target ClassificationN/A

    The target: KANSL2, gene name: KANSL2, also named as C12orf41, NSL2. Involved in histone H4-K16 acetylation; histone H4-K5 acetylation; and histone H4-K8 acetylation. Located in several cellular components, including actin cytoskeleton; cytosol; and nucleoplasm. Part of histone acetyltransferase complex. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.