Anti-MAGI1/ AIP-3/ AIP3 monoclonal antibody

Anti-MAGI1/ AIP-3/ AIP3 antibody for FACS & in-vivo assay

Target products collectionGo to MAGI1/MAGI1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2191-Ab-1/ GM-Tg-hg-MP2191-Ab-2Anti-Human MAGI1 monoclonal antibodyHuman
GM-Tg-rg-MP2191-Ab-1/ GM-Tg-rg-MP2191-Ab-2Anti-Rat MAGI1 monoclonal antibodyRat
GM-Tg-mg-MP2191-Ab-1/ GM-Tg-mg-MP2191-Ab-2Anti-Mouse MAGI1 monoclonal antibodyMouse
GM-Tg-cynog-MP2191-Ab-1/ GM-Tg-cynog-MP2191-Ab-2Anti-Cynomolgus/ Rhesus macaque MAGI1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2191-Ab-1/ GM-Tg-felg-MP2191-Ab-2Anti-Feline MAGI1 monoclonal antibodyFeline
GM-Tg-cang-MP2191-Ab-1/ GM-Tg-cang-MP2191-Ab-2Anti-Canine MAGI1 monoclonal antibodyCanine
GM-Tg-bovg-MP2191-Ab-1/ GM-Tg-bovg-MP2191-Ab-2Anti-Bovine MAGI1 monoclonal antibodyBovine
GM-Tg-equg-MP2191-Ab-1/ GM-Tg-equg-MP2191-Ab-2Anti-Equine MAGI1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2191-Ab-1/ GM-Tg-hg-MP2191-Ab-2; GM-Tg-rg-MP2191-Ab-1/ GM-Tg-rg-MP2191-Ab-2;
GM-Tg-mg-MP2191-Ab-1/ GM-Tg-mg-MP2191-Ab-2; GM-Tg-cynog-MP2191-Ab-1/ GM-Tg-cynog-MP2191-Ab-2;
GM-Tg-felg-MP2191-Ab-1/ GM-Tg-felg-MP2191-Ab-2; GM-Tg-cang-MP2191-Ab-1/ GM-Tg-cang-MP2191-Ab-2;
GM-Tg-bovg-MP2191-Ab-1/ GM-Tg-bovg-MP2191-Ab-2; GM-Tg-equg-MP2191-Ab-1/ GM-Tg-equg-MP2191-Ab-2
Products NameAnti-MAGI1 monoclonal antibody
Formatmab
Target NameMAGI1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MAGI1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MAGI1/ AIP-3/ AIP3 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2191
    Target NameMAGI1
    Gene ID9223,14924,500261,698092,476565,101086887,783484,100049816
    Gene Symbol and SynonymsAIP-3,AIP3,BAIAP1,BAP-1,BAP1,Gukmi1,MAGI-1,MAGI-1b,MAGI1,MAGI1c,Magi1d,mKIAA4129,TNRC19,WWP3
    Uniprot AccessionQ96QZ7,Q4L1J4
    Uniprot Entry NameMAGI1_HUMAN,MAGI1_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000151276
    Target ClassificationN/A

    The target: MAGI1, gene name: MAGI1, also named as AIP-3, AIP3, BAIAP1, BAP-1, BAP1, MAGI-1, Magi1d, TNRC19, WWP3. The protein encoded by this gene is a member of the membrane-associated guanylate kinase homologue (MAGUK) family. MAGUK proteins participate in the assembly of multiprotein complexes on the inner surface of the plasma membrane at regions of cell-cell contact. The product of this gene may play a role as scaffolding protein at cell-cell junctions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.