Anti-MCTS1/ MCT-1/ MCT1 monoclonal antibody

Anti-MCTS1/ MCT-1/ MCT1 antibody for FACS & in-vivo assay

Target products collectionGo to MCTS1/MCTS1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2196-Ab-1/ GM-Tg-hg-MP2196-Ab-2Anti-Human MCTS1 monoclonal antibodyHuman
GM-Tg-rg-MP2196-Ab-1/ GM-Tg-rg-MP2196-Ab-2Anti-Rat MCTS1 monoclonal antibodyRat
GM-Tg-mg-MP2196-Ab-1/ GM-Tg-mg-MP2196-Ab-2Anti-Mouse MCTS1 monoclonal antibodyMouse
GM-Tg-cynog-MP2196-Ab-1/ GM-Tg-cynog-MP2196-Ab-2Anti-Cynomolgus/ Rhesus macaque MCTS1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2196-Ab-1/ GM-Tg-felg-MP2196-Ab-2Anti-Feline MCTS1 monoclonal antibodyFeline
GM-Tg-cang-MP2196-Ab-1/ GM-Tg-cang-MP2196-Ab-2Anti-Canine MCTS1 monoclonal antibodyCanine
GM-Tg-bovg-MP2196-Ab-1/ GM-Tg-bovg-MP2196-Ab-2Anti-Bovine MCTS1 monoclonal antibodyBovine
GM-Tg-equg-MP2196-Ab-1/ GM-Tg-equg-MP2196-Ab-2Anti-Equine MCTS1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2196-Ab-1/ GM-Tg-hg-MP2196-Ab-2; GM-Tg-rg-MP2196-Ab-1/ GM-Tg-rg-MP2196-Ab-2;
GM-Tg-mg-MP2196-Ab-1/ GM-Tg-mg-MP2196-Ab-2; GM-Tg-cynog-MP2196-Ab-1/ GM-Tg-cynog-MP2196-Ab-2;
GM-Tg-felg-MP2196-Ab-1/ GM-Tg-felg-MP2196-Ab-2; GM-Tg-cang-MP2196-Ab-1/ GM-Tg-cang-MP2196-Ab-2;
GM-Tg-bovg-MP2196-Ab-1/ GM-Tg-bovg-MP2196-Ab-2; GM-Tg-equg-MP2196-Ab-1/ GM-Tg-equg-MP2196-Ab-2
Products NameAnti-MCTS1 monoclonal antibody
Formatmab
Target NameMCTS1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MCTS1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MCTS1/ MCT-1/ MCT1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP000376human MCTS1 Lentivirus particle
    ORF Viral VectorpGMLP000376human MCTS1 Lentivirus plasmid


    Target information

    Target IDGM-MP2196
    Target NameMCTS1
    Gene ID28985,68995,302500,696543,481038,101088064,508412,100629673
    Gene Symbol and Synonyms1500019M23Rik,MCT-1,MCT1,MCTS1
    Uniprot AccessionQ9ULC4,Q4G009,Q2KIE4
    Uniprot Entry NameMCTS1_HUMAN,MCTS1_RAT,MCTS1_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000232119
    Target ClassificationN/A

    The target: MCTS1, gene name: MCTS1, also named as MCT-1, MCT1. Predicted to enable translation initiation factor activity. Involved in IRES-dependent viral translational initiation; formation of translation preinitiation complex; and ribosome disassembly. Located in cytosol and plasma membrane. Colocalizes with cytosolic small ribosomal subunit. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.