Anti-MYO10 monoclonal antibody

Anti-MYO10 antibody for FACS & in-vivo assay

Target products collectionGo to MYO10/MYO10 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2208-Ab-1/ GM-Tg-hg-MP2208-Ab-2Anti-Human MYO10 monoclonal antibodyHuman
GM-Tg-rg-MP2208-Ab-1/ GM-Tg-rg-MP2208-Ab-2Anti-Rat MYO10 monoclonal antibodyRat
GM-Tg-mg-MP2208-Ab-1/ GM-Tg-mg-MP2208-Ab-2Anti-Mouse MYO10 monoclonal antibodyMouse
GM-Tg-cynog-MP2208-Ab-1/ GM-Tg-cynog-MP2208-Ab-2Anti-Cynomolgus/ Rhesus macaque MYO10 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2208-Ab-1/ GM-Tg-felg-MP2208-Ab-2Anti-Feline MYO10 monoclonal antibodyFeline
GM-Tg-cang-MP2208-Ab-1/ GM-Tg-cang-MP2208-Ab-2Anti-Canine MYO10 monoclonal antibodyCanine
GM-Tg-bovg-MP2208-Ab-1/ GM-Tg-bovg-MP2208-Ab-2Anti-Bovine MYO10 monoclonal antibodyBovine
GM-Tg-equg-MP2208-Ab-1/ GM-Tg-equg-MP2208-Ab-2Anti-Equine MYO10 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2208-Ab-1/ GM-Tg-hg-MP2208-Ab-2; GM-Tg-rg-MP2208-Ab-1/ GM-Tg-rg-MP2208-Ab-2;
GM-Tg-mg-MP2208-Ab-1/ GM-Tg-mg-MP2208-Ab-2; GM-Tg-cynog-MP2208-Ab-1/ GM-Tg-cynog-MP2208-Ab-2;
GM-Tg-felg-MP2208-Ab-1/ GM-Tg-felg-MP2208-Ab-2; GM-Tg-cang-MP2208-Ab-1/ GM-Tg-cang-MP2208-Ab-2;
GM-Tg-bovg-MP2208-Ab-1/ GM-Tg-bovg-MP2208-Ab-2; GM-Tg-equg-MP2208-Ab-1/ GM-Tg-equg-MP2208-Ab-2
Products NameAnti-MYO10 monoclonal antibody
Formatmab
Target NameMYO10
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-MYO10 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MYO10 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2208
    Target NameMYO10
    Gene ID4651,17909,310178,718002,489261,101088985,281935,100054475
    Gene Symbol and SynonymsD15Ertd600e,mKIAA0799,MYO10,myosin-X,MyoX
    Uniprot AccessionQ9HD67,D3ZJP6,P79114
    Uniprot Entry NameMYO10_HUMAN,MYO10_RAT,MYO10_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000145555
    Target ClassificationN/A

    The target: MYO10, gene name: MYO10, also named as . This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-10 (MYH10). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. This gene functions as an actin-based molecular motor and plays a role in integration of F-actin and microtubule cytoskeletons during meiosis. [provided by RefSeq, Dec 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.