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Anti-MYO1C/ MMI-beta/ MMIb monoclonal antibody
Anti-MYO1C/ MMI-beta/ MMIb antibody for FACS & in-vivo assay
Go to MYO1C/MYO1C products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2210-Ab-1/ GM-Tg-hg-MP2210-Ab-2 | Anti-Human MYO1C monoclonal antibody | Human |
| GM-Tg-rg-MP2210-Ab-1/ GM-Tg-rg-MP2210-Ab-2 | Anti-Rat MYO1C monoclonal antibody | Rat |
| GM-Tg-mg-MP2210-Ab-1/ GM-Tg-mg-MP2210-Ab-2 | Anti-Mouse MYO1C monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2210-Ab-1/ GM-Tg-cynog-MP2210-Ab-2 | Anti-Cynomolgus/ Rhesus macaque MYO1C monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2210-Ab-1/ GM-Tg-felg-MP2210-Ab-2 | Anti-Feline MYO1C monoclonal antibody | Feline |
| GM-Tg-cang-MP2210-Ab-1/ GM-Tg-cang-MP2210-Ab-2 | Anti-Canine MYO1C monoclonal antibody | Canine |
| GM-Tg-bovg-MP2210-Ab-1/ GM-Tg-bovg-MP2210-Ab-2 | Anti-Bovine MYO1C monoclonal antibody | Bovine |
| GM-Tg-equg-MP2210-Ab-1/ GM-Tg-equg-MP2210-Ab-2 | Anti-Equine MYO1C monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2210-Ab-1/ GM-Tg-hg-MP2210-Ab-2; GM-Tg-rg-MP2210-Ab-1/ GM-Tg-rg-MP2210-Ab-2; GM-Tg-mg-MP2210-Ab-1/ GM-Tg-mg-MP2210-Ab-2; GM-Tg-cynog-MP2210-Ab-1/ GM-Tg-cynog-MP2210-Ab-2; GM-Tg-felg-MP2210-Ab-1/ GM-Tg-felg-MP2210-Ab-2; GM-Tg-cang-MP2210-Ab-1/ GM-Tg-cang-MP2210-Ab-2; GM-Tg-bovg-MP2210-Ab-1/ GM-Tg-bovg-MP2210-Ab-2; GM-Tg-equg-MP2210-Ab-1/ GM-Tg-equg-MP2210-Ab-2 |
| Products Name | Anti-MYO1C monoclonal antibody |
| Format | mab |
| Target Name | MYO1C |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-MYO1C benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species MYO1C/ MMI-beta/ MMIb VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP2210 |
| Target Name | MYO1C |
| Gene ID | 4641,17913,65261,721217,100855443,101101176,281937,100059989 |
| Gene Symbol and Synonyms | mm1beta,MMI-beta,MMIb,MYO1C,MYO1E,MyoIC,myr2,NMI |
| Uniprot Accession | O00159,Q63355,Q27966 |
| Uniprot Entry Name | MYO1C_HUMAN,MYO1C_RAT,MYO1C_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000197879 |
| Target Classification | N/A |
The target: MYO1C, gene name: MYO1C, also named as MMI-beta, MMIb, NMI, myr2. This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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