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Protocol Library Download
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Anti-NSF1C/ NSFL1C/ P47 monoclonal antibody
Anti-NSF1C/ NSFL1C/ P47 antibody for FACS & in-vivo assay
Go to NSFL1C/NSFL1C products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2218-Ab-1/ GM-Tg-hg-MP2218-Ab-2 | Anti-Human NSFL1C monoclonal antibody | Human |
| GM-Tg-rg-MP2218-Ab-1/ GM-Tg-rg-MP2218-Ab-2 | Anti-Rat NSFL1C monoclonal antibody | Rat |
| GM-Tg-mg-MP2218-Ab-1/ GM-Tg-mg-MP2218-Ab-2 | Anti-Mouse NSFL1C monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2218-Ab-1/ GM-Tg-cynog-MP2218-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NSFL1C monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2218-Ab-1/ GM-Tg-felg-MP2218-Ab-2 | Anti-Feline NSFL1C monoclonal antibody | Feline |
| GM-Tg-cang-MP2218-Ab-1/ GM-Tg-cang-MP2218-Ab-2 | Anti-Canine NSFL1C monoclonal antibody | Canine |
| GM-Tg-bovg-MP2218-Ab-1/ GM-Tg-bovg-MP2218-Ab-2 | Anti-Bovine NSFL1C monoclonal antibody | Bovine |
| GM-Tg-equg-MP2218-Ab-1/ GM-Tg-equg-MP2218-Ab-2 | Anti-Equine NSFL1C monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2218-Ab-1/ GM-Tg-hg-MP2218-Ab-2; GM-Tg-rg-MP2218-Ab-1/ GM-Tg-rg-MP2218-Ab-2; GM-Tg-mg-MP2218-Ab-1/ GM-Tg-mg-MP2218-Ab-2; GM-Tg-cynog-MP2218-Ab-1/ GM-Tg-cynog-MP2218-Ab-2; GM-Tg-felg-MP2218-Ab-1/ GM-Tg-felg-MP2218-Ab-2; GM-Tg-cang-MP2218-Ab-1/ GM-Tg-cang-MP2218-Ab-2; GM-Tg-bovg-MP2218-Ab-1/ GM-Tg-bovg-MP2218-Ab-2; GM-Tg-equg-MP2218-Ab-1/ GM-Tg-equg-MP2218-Ab-2 |
| Products Name | Anti-NSFL1C monoclonal antibody |
| Format | mab |
| Target Name | NSFL1C |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-NSFL1C benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species NSF1C/ NSFL1C/ P47 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP2218 |
| Target Name | NSFL1C |
| Gene ID | 55968,386649,83809,715743,100685961,101100120,526612,100067632 |
| Gene Symbol and Synonyms | dJ776F14.1,Munc-18c,NSFL1C,P47,Stxbp3a,UBX1,UBXD10,UBXN2C,XY40 |
| Uniprot Accession | Q9UNZ2,O35987,Q3SZC4 |
| Uniprot Entry Name | NSF1C_HUMAN,NSF1C_RAT,NSF1C_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000088833 |
| Target Classification | N/A |
The target: NSFL1C, gene name: NSFL1C, also named as P47, UBX1, UBXD10, UBXN2C, dJ776F14.1. N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. A trimer of the protein encoded by this gene binds a hexamer of cytosolic p97 and is required for p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, May 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
