Anti-NSF1C/ NSFL1C/ P47 monoclonal antibody

Anti-NSF1C/ NSFL1C/ P47 antibody for FACS & in-vivo assay

Target products collectionGo to NSFL1C/NSFL1C products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2218-Ab-1/ GM-Tg-hg-MP2218-Ab-2Anti-Human NSFL1C monoclonal antibodyHuman
GM-Tg-rg-MP2218-Ab-1/ GM-Tg-rg-MP2218-Ab-2Anti-Rat NSFL1C monoclonal antibodyRat
GM-Tg-mg-MP2218-Ab-1/ GM-Tg-mg-MP2218-Ab-2Anti-Mouse NSFL1C monoclonal antibodyMouse
GM-Tg-cynog-MP2218-Ab-1/ GM-Tg-cynog-MP2218-Ab-2Anti-Cynomolgus/ Rhesus macaque NSFL1C monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2218-Ab-1/ GM-Tg-felg-MP2218-Ab-2Anti-Feline NSFL1C monoclonal antibodyFeline
GM-Tg-cang-MP2218-Ab-1/ GM-Tg-cang-MP2218-Ab-2Anti-Canine NSFL1C monoclonal antibodyCanine
GM-Tg-bovg-MP2218-Ab-1/ GM-Tg-bovg-MP2218-Ab-2Anti-Bovine NSFL1C monoclonal antibodyBovine
GM-Tg-equg-MP2218-Ab-1/ GM-Tg-equg-MP2218-Ab-2Anti-Equine NSFL1C monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2218-Ab-1/ GM-Tg-hg-MP2218-Ab-2; GM-Tg-rg-MP2218-Ab-1/ GM-Tg-rg-MP2218-Ab-2;
GM-Tg-mg-MP2218-Ab-1/ GM-Tg-mg-MP2218-Ab-2; GM-Tg-cynog-MP2218-Ab-1/ GM-Tg-cynog-MP2218-Ab-2;
GM-Tg-felg-MP2218-Ab-1/ GM-Tg-felg-MP2218-Ab-2; GM-Tg-cang-MP2218-Ab-1/ GM-Tg-cang-MP2218-Ab-2;
GM-Tg-bovg-MP2218-Ab-1/ GM-Tg-bovg-MP2218-Ab-2; GM-Tg-equg-MP2218-Ab-1/ GM-Tg-equg-MP2218-Ab-2
Products NameAnti-NSFL1C monoclonal antibody
Formatmab
Target NameNSFL1C
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-NSFL1C benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species NSF1C/ NSFL1C/ P47 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2218
    Target NameNSFL1C
    Gene ID55968,386649,83809,715743,100685961,101100120,526612,100067632
    Gene Symbol and SynonymsdJ776F14.1,Munc-18c,NSFL1C,P47,Stxbp3a,UBX1,UBXD10,UBXN2C,XY40
    Uniprot AccessionQ9UNZ2,O35987,Q3SZC4
    Uniprot Entry NameNSF1C_HUMAN,NSF1C_RAT,NSF1C_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000088833
    Target ClassificationN/A

    The target: NSFL1C, gene name: NSFL1C, also named as P47, UBX1, UBXD10, UBXN2C, dJ776F14.1. N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. A trimer of the protein encoded by this gene binds a hexamer of cytosolic p97 and is required for p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, May 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.