Anti-OSBL6/ OSBPL6/ ORP6 monoclonal antibody

Anti-OSBL6/ OSBPL6/ ORP6 antibody for FACS & in-vivo assay

Target products collectionGo to OSBPL6/OSBPL6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2224-Ab-1/ GM-Tg-hg-MP2224-Ab-2Anti-Human OSBPL6 monoclonal antibodyHuman
GM-Tg-rg-MP2224-Ab-1/ GM-Tg-rg-MP2224-Ab-2Anti-Rat OSBPL6 monoclonal antibodyRat
GM-Tg-mg-MP2224-Ab-1/ GM-Tg-mg-MP2224-Ab-2Anti-Mouse OSBPL6 monoclonal antibodyMouse
GM-Tg-cynog-MP2224-Ab-1/ GM-Tg-cynog-MP2224-Ab-2Anti-Cynomolgus/ Rhesus macaque OSBPL6 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2224-Ab-1/ GM-Tg-felg-MP2224-Ab-2Anti-Feline OSBPL6 monoclonal antibodyFeline
GM-Tg-cang-MP2224-Ab-1/ GM-Tg-cang-MP2224-Ab-2Anti-Canine OSBPL6 monoclonal antibodyCanine
GM-Tg-bovg-MP2224-Ab-1/ GM-Tg-bovg-MP2224-Ab-2Anti-Bovine OSBPL6 monoclonal antibodyBovine
GM-Tg-equg-MP2224-Ab-1/ GM-Tg-equg-MP2224-Ab-2Anti-Equine OSBPL6 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2224-Ab-1/ GM-Tg-hg-MP2224-Ab-2; GM-Tg-rg-MP2224-Ab-1/ GM-Tg-rg-MP2224-Ab-2;
GM-Tg-mg-MP2224-Ab-1/ GM-Tg-mg-MP2224-Ab-2; GM-Tg-cynog-MP2224-Ab-1/ GM-Tg-cynog-MP2224-Ab-2;
GM-Tg-felg-MP2224-Ab-1/ GM-Tg-felg-MP2224-Ab-2; GM-Tg-cang-MP2224-Ab-1/ GM-Tg-cang-MP2224-Ab-2;
GM-Tg-bovg-MP2224-Ab-1/ GM-Tg-bovg-MP2224-Ab-2; GM-Tg-equg-MP2224-Ab-1/ GM-Tg-equg-MP2224-Ab-2
Products NameAnti-OSBPL6 monoclonal antibody
Formatmab
Target NameOSBPL6
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-OSBPL6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species OSBL6/ OSBPL6/ ORP6 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2224
    Target NameOSBPL6
    Gene ID114880,99031,311129,708349,478816,101100746,533634,100067212
    Gene Symbol and Synonyms1110062M20Rik,mKIAA4128,ORP-6,ORP6,OSBPL6
    Uniprot AccessionQ9BZF3
    Uniprot Entry NameOSBL6_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000079156
    Target ClassificationN/A

    The target: OSBPL6, gene name: OSBPL6, also named as ORP6. This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.