Anti-OSGEP/ GAMOS3/ GCPL1 monoclonal antibody

Anti-OSGEP/ GAMOS3/ GCPL1 antibody for FACS & in-vivo assay

Target products collectionGo to OSGEP/OSGEP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2226-Ab-1/ GM-Tg-hg-MP2226-Ab-2Anti-Human OSGEP monoclonal antibodyHuman
GM-Tg-rg-MP2226-Ab-1/ GM-Tg-rg-MP2226-Ab-2Anti-Rat OSGEP monoclonal antibodyRat
GM-Tg-mg-MP2226-Ab-1/ GM-Tg-mg-MP2226-Ab-2Anti-Mouse OSGEP monoclonal antibodyMouse
GM-Tg-cynog-MP2226-Ab-1/ GM-Tg-cynog-MP2226-Ab-2Anti-Cynomolgus/ Rhesus macaque OSGEP monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2226-Ab-1/ GM-Tg-felg-MP2226-Ab-2Anti-Feline OSGEP monoclonal antibodyFeline
GM-Tg-cang-MP2226-Ab-1/ GM-Tg-cang-MP2226-Ab-2Anti-Canine OSGEP monoclonal antibodyCanine
GM-Tg-bovg-MP2226-Ab-1/ GM-Tg-bovg-MP2226-Ab-2Anti-Bovine OSGEP monoclonal antibodyBovine
GM-Tg-equg-MP2226-Ab-1/ GM-Tg-equg-MP2226-Ab-2Anti-Equine OSGEP monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2226-Ab-1/ GM-Tg-hg-MP2226-Ab-2; GM-Tg-rg-MP2226-Ab-1/ GM-Tg-rg-MP2226-Ab-2;
GM-Tg-mg-MP2226-Ab-1/ GM-Tg-mg-MP2226-Ab-2; GM-Tg-cynog-MP2226-Ab-1/ GM-Tg-cynog-MP2226-Ab-2;
GM-Tg-felg-MP2226-Ab-1/ GM-Tg-felg-MP2226-Ab-2; GM-Tg-cang-MP2226-Ab-1/ GM-Tg-cang-MP2226-Ab-2;
GM-Tg-bovg-MP2226-Ab-1/ GM-Tg-bovg-MP2226-Ab-2; GM-Tg-equg-MP2226-Ab-1/ GM-Tg-equg-MP2226-Ab-2
Products NameAnti-OSGEP monoclonal antibody
Formatmab
Target NameOSGEP
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-OSGEP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species OSGEP/ GAMOS3/ GCPL1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP004420human OSGEP Lentivirus plasmid
    ORF Viral VectorvGMLP004420human OSGEP Lentivirus particle
    ORF Viral VectorpGMLPm003519mouse Osgep Lentivirus plasmid
    ORF Viral VectorvGMLPm003519mouse Osgep Lentivirus particle


    Target information

    Target IDGM-MP2226
    Target NameOSGEP
    Gene ID55644,66246,290028,702512,100687555,101101062,507512,100058606
    Gene Symbol and Synonyms1500019L24Rik,GAMOS3,GCPL-1,GCPL1,KAE1,OSGEP,OSGEP1,PRSMG1,TCS3
    Uniprot AccessionQ9NPF4,Q9WVS2,Q0VCI1
    Uniprot Entry NameOSGEP_HUMAN,OSGEP_RAT,OSGEP_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000092094
    Target ClassificationN/A

    The target: OSGEP, gene name: OSGEP, also named as GAMOS3, GCPL1, KAE11, PRSMG1, TCS3, OSGEP. Predicted to enable N(6)-L-threonylcarbamoyladenine synthase activity and metal ion binding activity. Involved in tRNA threonylcarbamoyladenosine modification. Located in cytoplasm; nuclear speck; and plasma membrane. Part of EKC/KEOPS complex. Implicated in Galloway-Mowat syndrome 3. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.