Anti-PALLD/ CGI-151/ CGI151 monoclonal antibody

Anti-PALLD/ CGI-151/ CGI151 antibody for FACS & in-vivo assay

Target products collectionGo to PALLD/PALLD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2230-Ab-1/ GM-Tg-hg-MP2230-Ab-2Anti-Human PALLD monoclonal antibodyHuman
GM-Tg-rg-MP2230-Ab-1/ GM-Tg-rg-MP2230-Ab-2Anti-Rat PALLD monoclonal antibodyRat
GM-Tg-mg-MP2230-Ab-1/ GM-Tg-mg-MP2230-Ab-2Anti-Mouse PALLD monoclonal antibodyMouse
GM-Tg-cynog-MP2230-Ab-1/ GM-Tg-cynog-MP2230-Ab-2Anti-Cynomolgus/ Rhesus macaque PALLD monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2230-Ab-1/ GM-Tg-felg-MP2230-Ab-2Anti-Feline PALLD monoclonal antibodyFeline
GM-Tg-cang-MP2230-Ab-1/ GM-Tg-cang-MP2230-Ab-2Anti-Canine PALLD monoclonal antibodyCanine
GM-Tg-bovg-MP2230-Ab-1/ GM-Tg-bovg-MP2230-Ab-2Anti-Bovine PALLD monoclonal antibodyBovine
GM-Tg-equg-MP2230-Ab-1/ GM-Tg-equg-MP2230-Ab-2Anti-Equine PALLD monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2230-Ab-1/ GM-Tg-hg-MP2230-Ab-2; GM-Tg-rg-MP2230-Ab-1/ GM-Tg-rg-MP2230-Ab-2;
GM-Tg-mg-MP2230-Ab-1/ GM-Tg-mg-MP2230-Ab-2; GM-Tg-cynog-MP2230-Ab-1/ GM-Tg-cynog-MP2230-Ab-2;
GM-Tg-felg-MP2230-Ab-1/ GM-Tg-felg-MP2230-Ab-2; GM-Tg-cang-MP2230-Ab-1/ GM-Tg-cang-MP2230-Ab-2;
GM-Tg-bovg-MP2230-Ab-1/ GM-Tg-bovg-MP2230-Ab-2; GM-Tg-equg-MP2230-Ab-1/ GM-Tg-equg-MP2230-Ab-2
Products NameAnti-PALLD monoclonal antibody
Formatmab
Target NamePALLD
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PALLD benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PALLD/ CGI-151/ CGI151 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2230
    Target NamePALLD
    Gene ID23022,72333,693824,477351,101094503,617678,100061451
    Gene Symbol and Synonyms2410003B16Rik,6030492A02,CGI-151,CGI151,MYN,PALLD,PNCA1,SIH002
    Uniprot AccessionQ8WX93
    Uniprot Entry NamePALLD_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000129116
    Target ClassificationN/A

    The target: PALLD, gene name: PALLD, also named as CGI-151, CGI151, MYN, PNCA1, SIH002. This gene encodes a cytoskeletal protein that is required for organizing the actin cytoskeleton. The protein is a component of actin-containing microfilaments, and it is involved in the control of cell shape, adhesion, and contraction. Polymorphisms in this gene are associated with a susceptibility to pancreatic cancer type 1, and also with a risk for myocardial infarction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.