Anti-PALM monoclonal antibody

Anti-PALM antibody for FACS & in-vivo assay

Target products collectionGo to PALM/PALM products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2231-Ab-1/ GM-Tg-hg-MP2231-Ab-2Anti-Human PALM monoclonal antibodyHuman
GM-Tg-rg-MP2231-Ab-1/ GM-Tg-rg-MP2231-Ab-2Anti-Rat PALM monoclonal antibodyRat
GM-Tg-mg-MP2231-Ab-1/ GM-Tg-mg-MP2231-Ab-2Anti-Mouse PALM monoclonal antibodyMouse
GM-Tg-cynog-MP2231-Ab-1/ GM-Tg-cynog-MP2231-Ab-2Anti-Cynomolgus/ Rhesus macaque PALM monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2231-Ab-1/ GM-Tg-felg-MP2231-Ab-2Anti-Feline PALM monoclonal antibodyFeline
GM-Tg-cang-MP2231-Ab-1/ GM-Tg-cang-MP2231-Ab-2Anti-Canine PALM monoclonal antibodyCanine
GM-Tg-bovg-MP2231-Ab-1/ GM-Tg-bovg-MP2231-Ab-2Anti-Bovine PALM monoclonal antibodyBovine
GM-Tg-equg-MP2231-Ab-1/ GM-Tg-equg-MP2231-Ab-2Anti-Equine PALM monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2231-Ab-1/ GM-Tg-hg-MP2231-Ab-2; GM-Tg-rg-MP2231-Ab-1/ GM-Tg-rg-MP2231-Ab-2;
GM-Tg-mg-MP2231-Ab-1/ GM-Tg-mg-MP2231-Ab-2; GM-Tg-cynog-MP2231-Ab-1/ GM-Tg-cynog-MP2231-Ab-2;
GM-Tg-felg-MP2231-Ab-1/ GM-Tg-felg-MP2231-Ab-2; GM-Tg-cang-MP2231-Ab-1/ GM-Tg-cang-MP2231-Ab-2;
GM-Tg-bovg-MP2231-Ab-1/ GM-Tg-bovg-MP2231-Ab-2; GM-Tg-equg-MP2231-Ab-1/ GM-Tg-equg-MP2231-Ab-2
Products NameAnti-PALM monoclonal antibody
Formatmab
Target NamePALM
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PALM benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PALM VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2231
    Target NamePALM
    Gene ID5064,18483,170673,721111,485098,101092243,786096,106781146
    Gene Symbol and SynonymsPALM,PALM1
    Uniprot AccessionO75781,Q920Q0
    Uniprot Entry NamePALM_HUMAN,PALM_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000099864
    Target ClassificationN/A

    The target: PALM, gene name: PALM, also named as . This gene encodes a member of the paralemmin protein family. The product of this gene is a prenylated and palmitoylated phosphoprotein that associates with the cytoplasmic face of plasma membranes and is implicated in plasma membrane dynamics in neurons and other cell types. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.