Anti-INADL/ PATJ/ Cipp monoclonal antibody

Anti-INADL/ PATJ/ Cipp antibody for FACS & in-vivo assay

Target products collectionGo to PATJ/PATJ products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2236-Ab-1/ GM-Tg-hg-MP2236-Ab-2Anti-Human PATJ monoclonal antibodyHuman
GM-Tg-rg-MP2236-Ab-1/ GM-Tg-rg-MP2236-Ab-2Anti-Rat PATJ monoclonal antibodyRat
GM-Tg-mg-MP2236-Ab-1/ GM-Tg-mg-MP2236-Ab-2Anti-Mouse PATJ monoclonal antibodyMouse
GM-Tg-cynog-MP2236-Ab-1/ GM-Tg-cynog-MP2236-Ab-2Anti-Cynomolgus/ Rhesus macaque PATJ monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2236-Ab-1/ GM-Tg-felg-MP2236-Ab-2Anti-Feline PATJ monoclonal antibodyFeline
GM-Tg-cang-MP2236-Ab-1/ GM-Tg-cang-MP2236-Ab-2Anti-Canine PATJ monoclonal antibodyCanine
GM-Tg-bovg-MP2236-Ab-1/ GM-Tg-bovg-MP2236-Ab-2Anti-Bovine PATJ monoclonal antibodyBovine
GM-Tg-equg-MP2236-Ab-1/ GM-Tg-equg-MP2236-Ab-2Anti-Equine PATJ monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2236-Ab-1/ GM-Tg-hg-MP2236-Ab-2; GM-Tg-rg-MP2236-Ab-1/ GM-Tg-rg-MP2236-Ab-2;
GM-Tg-mg-MP2236-Ab-1/ GM-Tg-mg-MP2236-Ab-2; GM-Tg-cynog-MP2236-Ab-1/ GM-Tg-cynog-MP2236-Ab-2;
GM-Tg-felg-MP2236-Ab-1/ GM-Tg-felg-MP2236-Ab-2; GM-Tg-cang-MP2236-Ab-1/ GM-Tg-cang-MP2236-Ab-2;
GM-Tg-bovg-MP2236-Ab-1/ GM-Tg-bovg-MP2236-Ab-2; GM-Tg-equg-MP2236-Ab-1/ GM-Tg-equg-MP2236-Ab-2
Products NameAnti-PATJ monoclonal antibody
Formatmab
Target NamePATJ
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PATJ benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species INADL/ PATJ/ Cipp VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2236
    Target NamePATJ
    Gene ID10207,12695,140581,719263,479550,101098731,536993,100070486
    Gene Symbol and SynonymsCipp,hINADL,InaD-like,INADL,Inadl2,PATJ,RGD1565362
    Uniprot AccessionQ8NI35,F1MAD2,E2QYC9
    Uniprot Entry NameINADL_HUMAN,INADL_RAT,INADL_CANLF
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000132849
    Target ClassificationN/A

    The target: PATJ, gene name: PATJ, also named as Cipp, INADL, InaD-like, hINADL. This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.