Anti-HAP28/ PDAP1/ HASPP28 monoclonal antibody

Anti-HAP28/ PDAP1/ HASPP28 antibody for FACS & in-vivo assay

Target products collectionGo to PDAP1/PDAP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2238-Ab-1/ GM-Tg-hg-MP2238-Ab-2Anti-Human PDAP1 monoclonal antibodyHuman
GM-Tg-rg-MP2238-Ab-1/ GM-Tg-rg-MP2238-Ab-2Anti-Rat PDAP1 monoclonal antibodyRat
GM-Tg-mg-MP2238-Ab-1/ GM-Tg-mg-MP2238-Ab-2Anti-Mouse PDAP1 monoclonal antibodyMouse
GM-Tg-cynog-MP2238-Ab-1/ GM-Tg-cynog-MP2238-Ab-2Anti-Cynomolgus/ Rhesus macaque PDAP1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2238-Ab-1/ GM-Tg-felg-MP2238-Ab-2Anti-Feline PDAP1 monoclonal antibodyFeline
GM-Tg-cang-MP2238-Ab-1/ GM-Tg-cang-MP2238-Ab-2Anti-Canine PDAP1 monoclonal antibodyCanine
GM-Tg-bovg-MP2238-Ab-1/ GM-Tg-bovg-MP2238-Ab-2Anti-Bovine PDAP1 monoclonal antibodyBovine
GM-Tg-equg-MP2238-Ab-1/ GM-Tg-equg-MP2238-Ab-2Anti-Equine PDAP1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2238-Ab-1/ GM-Tg-hg-MP2238-Ab-2; GM-Tg-rg-MP2238-Ab-1/ GM-Tg-rg-MP2238-Ab-2;
GM-Tg-mg-MP2238-Ab-1/ GM-Tg-mg-MP2238-Ab-2; GM-Tg-cynog-MP2238-Ab-1/ GM-Tg-cynog-MP2238-Ab-2;
GM-Tg-felg-MP2238-Ab-1/ GM-Tg-felg-MP2238-Ab-2; GM-Tg-cang-MP2238-Ab-1/ GM-Tg-cang-MP2238-Ab-2;
GM-Tg-bovg-MP2238-Ab-1/ GM-Tg-bovg-MP2238-Ab-2; GM-Tg-equg-MP2238-Ab-1/ GM-Tg-equg-MP2238-Ab-2
Products NameAnti-PDAP1 monoclonal antibody
Formatmab
Target NamePDAP1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PDAP1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species HAP28/ PDAP1/ HASPP28 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2238
    Target NamePDAP1
    Gene ID11333,231887,64527,707779,489861,101084923,100139074,100063675
    Gene Symbol and SynonymsHASPP28,PAP,PAP1,PDAP1
    Uniprot AccessionQ13442,Q62785
    Uniprot Entry NameHAP28_HUMAN,HAP28_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000106244
    Target ClassificationN/A

    The target: PDAP1, gene name: PDAP1, also named as HASPP28, PAP, PAP1. The protein encoded by this gene is a phosphoprotein that may upregulate the PDGFA-stimulated growth of fibroblasts and also downregulate the mitogenicity of PDGFB. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. [provided by RefSeq, Dec 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.