Anti-PDZD2/ AIPC/ PAPIN monoclonal antibody

Anti-PDZD2/ AIPC/ PAPIN antibody for FACS & in-vivo assay

Target products collectionGo to PDZD2/PDZD2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2239-Ab-1/ GM-Tg-hg-MP2239-Ab-2Anti-Human PDZD2 monoclonal antibodyHuman
GM-Tg-rg-MP2239-Ab-1/ GM-Tg-rg-MP2239-Ab-2Anti-Rat PDZD2 monoclonal antibodyRat
GM-Tg-mg-MP2239-Ab-1/ GM-Tg-mg-MP2239-Ab-2Anti-Mouse PDZD2 monoclonal antibodyMouse
GM-Tg-cynog-MP2239-Ab-1/ GM-Tg-cynog-MP2239-Ab-2Anti-Cynomolgus/ Rhesus macaque PDZD2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2239-Ab-1/ GM-Tg-felg-MP2239-Ab-2Anti-Feline PDZD2 monoclonal antibodyFeline
GM-Tg-cang-MP2239-Ab-1/ GM-Tg-cang-MP2239-Ab-2Anti-Canine PDZD2 monoclonal antibodyCanine
GM-Tg-bovg-MP2239-Ab-1/ GM-Tg-bovg-MP2239-Ab-2Anti-Bovine PDZD2 monoclonal antibodyBovine
GM-Tg-equg-MP2239-Ab-1/ GM-Tg-equg-MP2239-Ab-2Anti-Equine PDZD2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2239-Ab-1/ GM-Tg-hg-MP2239-Ab-2; GM-Tg-rg-MP2239-Ab-1/ GM-Tg-rg-MP2239-Ab-2;
GM-Tg-mg-MP2239-Ab-1/ GM-Tg-mg-MP2239-Ab-2; GM-Tg-cynog-MP2239-Ab-1/ GM-Tg-cynog-MP2239-Ab-2;
GM-Tg-felg-MP2239-Ab-1/ GM-Tg-felg-MP2239-Ab-2; GM-Tg-cang-MP2239-Ab-1/ GM-Tg-cang-MP2239-Ab-2;
GM-Tg-bovg-MP2239-Ab-1/ GM-Tg-bovg-MP2239-Ab-2; GM-Tg-equg-MP2239-Ab-1/ GM-Tg-equg-MP2239-Ab-2
Products NameAnti-PDZD2 monoclonal antibody
Formatmab
Target NamePDZD2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PDZD2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PDZD2/ AIPC/ PAPIN VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2239
    Target NamePDZD2
    Gene ID23037,68070,65034,696141,479373,101100368,516852,100068665
    Gene Symbol and Synonyms4930537L06Rik,A930022H17Rik,AIPC,Gm21706,Gm82,PAPIN,PDZD2,PDZK3,PIN1
    Uniprot AccessionO15018,Q9QZR8
    Uniprot Entry NamePDZD2_HUMAN,PDZD2_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000133401
    Target ClassificationN/A

    The target: PDZD2, gene name: PDZD2, also named as AIPC, PAPIN, PDZK3, PIN1. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq, Dec 2015].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.