Anti-P4K2A/ PI4K2A/ PI4KII monoclonal antibody

Anti-P4K2A/ PI4K2A/ PI4KII antibody for FACS & in-vivo assay

Target products collectionGo to PI4K2A/PI4K2A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2240-Ab-1/ GM-Tg-hg-MP2240-Ab-2Anti-Human PI4K2A monoclonal antibodyHuman
GM-Tg-rg-MP2240-Ab-1/ GM-Tg-rg-MP2240-Ab-2Anti-Rat PI4K2A monoclonal antibodyRat
GM-Tg-mg-MP2240-Ab-1/ GM-Tg-mg-MP2240-Ab-2Anti-Mouse PI4K2A monoclonal antibodyMouse
GM-Tg-cynog-MP2240-Ab-1/ GM-Tg-cynog-MP2240-Ab-2Anti-Cynomolgus/ Rhesus macaque PI4K2A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2240-Ab-1/ GM-Tg-felg-MP2240-Ab-2Anti-Feline PI4K2A monoclonal antibodyFeline
GM-Tg-cang-MP2240-Ab-1/ GM-Tg-cang-MP2240-Ab-2Anti-Canine PI4K2A monoclonal antibodyCanine
GM-Tg-bovg-MP2240-Ab-1/ GM-Tg-bovg-MP2240-Ab-2Anti-Bovine PI4K2A monoclonal antibodyBovine
GM-Tg-equg-MP2240-Ab-1/ GM-Tg-equg-MP2240-Ab-2Anti-Equine PI4K2A monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2240-Ab-1/ GM-Tg-hg-MP2240-Ab-2; GM-Tg-rg-MP2240-Ab-1/ GM-Tg-rg-MP2240-Ab-2;
GM-Tg-mg-MP2240-Ab-1/ GM-Tg-mg-MP2240-Ab-2; GM-Tg-cynog-MP2240-Ab-1/ GM-Tg-cynog-MP2240-Ab-2;
GM-Tg-felg-MP2240-Ab-1/ GM-Tg-felg-MP2240-Ab-2; GM-Tg-cang-MP2240-Ab-1/ GM-Tg-cang-MP2240-Ab-2;
GM-Tg-bovg-MP2240-Ab-1/ GM-Tg-bovg-MP2240-Ab-2; GM-Tg-equg-MP2240-Ab-1/ GM-Tg-equg-MP2240-Ab-2
Products NameAnti-PI4K2A monoclonal antibody
Formatmab
Target NamePI4K2A
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PI4K2A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species P4K2A/ PI4K2A/ PI4KII VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2240
    Target NamePI4K2A
    Gene ID55361,84095,114554,707201,486824,101088190,507860,100070680
    Gene Symbol and SynonymsPi4k2,PI4K2A,PI4KII,PIK42A
    Uniprot AccessionQ9BTU6,Q99M64
    Uniprot Entry NameP4K2A_HUMAN,P4K2A_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000155252
    Target ClassificationN/A

    The target: PI4K2A, gene name: PI4K2A, also named as PI4KII, PIK42A. Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs (Barylko et al., 2001 [PubMed 11244087]).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.