Anti-PLIN4/ KIAA1881/ S3-12 monoclonal antibody

Anti-PLIN4/ KIAA1881/ S3-12 antibody for FACS & in-vivo assay

Target products collectionGo to PLIN4/PLIN4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2252-Ab-1/ GM-Tg-hg-MP2252-Ab-2Anti-Human PLIN4 monoclonal antibodyHuman
GM-Tg-rg-MP2252-Ab-1/ GM-Tg-rg-MP2252-Ab-2Anti-Rat PLIN4 monoclonal antibodyRat
GM-Tg-mg-MP2252-Ab-1/ GM-Tg-mg-MP2252-Ab-2Anti-Mouse PLIN4 monoclonal antibodyMouse
GM-Tg-cynog-MP2252-Ab-1/ GM-Tg-cynog-MP2252-Ab-2Anti-Cynomolgus/ Rhesus macaque PLIN4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2252-Ab-1/ GM-Tg-felg-MP2252-Ab-2Anti-Feline PLIN4 monoclonal antibodyFeline
GM-Tg-cang-MP2252-Ab-1/ GM-Tg-cang-MP2252-Ab-2Anti-Canine PLIN4 monoclonal antibodyCanine
GM-Tg-bovg-MP2252-Ab-1/ GM-Tg-bovg-MP2252-Ab-2Anti-Bovine PLIN4 monoclonal antibodyBovine
GM-Tg-equg-MP2252-Ab-1/ GM-Tg-equg-MP2252-Ab-2Anti-Equine PLIN4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2252-Ab-1/ GM-Tg-hg-MP2252-Ab-2; GM-Tg-rg-MP2252-Ab-1/ GM-Tg-rg-MP2252-Ab-2;
GM-Tg-mg-MP2252-Ab-1/ GM-Tg-mg-MP2252-Ab-2; GM-Tg-cynog-MP2252-Ab-1/ GM-Tg-cynog-MP2252-Ab-2;
GM-Tg-felg-MP2252-Ab-1/ GM-Tg-felg-MP2252-Ab-2; GM-Tg-cang-MP2252-Ab-1/ GM-Tg-cang-MP2252-Ab-2;
GM-Tg-bovg-MP2252-Ab-1/ GM-Tg-bovg-MP2252-Ab-2; GM-Tg-equg-MP2252-Ab-1/ GM-Tg-equg-MP2252-Ab-2
Products NameAnti-PLIN4 monoclonal antibody
Formatmab
Target NamePLIN4
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PLIN4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PLIN4/ KIAA1881/ S3-12 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2252
    Target NamePLIN4
    Gene ID729359,57435,363331,693610,491467,101081609,107131384,111774181
    Gene Symbol and SynonymsKIAA1881,mKIAA1881,PLIN4,S3-12
    Uniprot AccessionQ96Q06
    Uniprot Entry NamePLIN4_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000167676
    Target ClassificationN/A

    The target: PLIN4, gene name: PLIN4, also named as KIAA1881, S3-12. Members of the perilipin family, such as PLIN4, coat intracellular lipid storage droplets (Wolins et al., 2003 [PubMed 12840023]).[supplied by OMIM, Feb 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.