Anti-VIP1/ PPIP5K1/ HISPPD2A monoclonal antibody

Anti-VIP1/ PPIP5K1/ HISPPD2A antibody for FACS & in-vivo assay

Target products collectionGo to PPIP5K1/PPIP5K1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2260-Ab-1/ GM-Tg-hg-MP2260-Ab-2Anti-Human PPIP5K1 monoclonal antibodyHuman
GM-Tg-rg-MP2260-Ab-1/ GM-Tg-rg-MP2260-Ab-2Anti-Rat PPIP5K1 monoclonal antibodyRat
GM-Tg-mg-MP2260-Ab-1/ GM-Tg-mg-MP2260-Ab-2Anti-Mouse PPIP5K1 monoclonal antibodyMouse
GM-Tg-cynog-MP2260-Ab-1/ GM-Tg-cynog-MP2260-Ab-2Anti-Cynomolgus/ Rhesus macaque PPIP5K1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2260-Ab-1/ GM-Tg-felg-MP2260-Ab-2Anti-Feline PPIP5K1 monoclonal antibodyFeline
GM-Tg-cang-MP2260-Ab-1/ GM-Tg-cang-MP2260-Ab-2Anti-Canine PPIP5K1 monoclonal antibodyCanine
GM-Tg-bovg-MP2260-Ab-1/ GM-Tg-bovg-MP2260-Ab-2Anti-Bovine PPIP5K1 monoclonal antibodyBovine
GM-Tg-equg-MP2260-Ab-1/ GM-Tg-equg-MP2260-Ab-2Anti-Equine PPIP5K1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2260-Ab-1/ GM-Tg-hg-MP2260-Ab-2; GM-Tg-rg-MP2260-Ab-1/ GM-Tg-rg-MP2260-Ab-2;
GM-Tg-mg-MP2260-Ab-1/ GM-Tg-mg-MP2260-Ab-2; GM-Tg-cynog-MP2260-Ab-1/ GM-Tg-cynog-MP2260-Ab-2;
GM-Tg-felg-MP2260-Ab-1/ GM-Tg-felg-MP2260-Ab-2; GM-Tg-cang-MP2260-Ab-1/ GM-Tg-cang-MP2260-Ab-2;
GM-Tg-bovg-MP2260-Ab-1/ GM-Tg-bovg-MP2260-Ab-2; GM-Tg-equg-MP2260-Ab-1/ GM-Tg-equg-MP2260-Ab-2
Products NameAnti-PPIP5K1 monoclonal antibody
Formatmab
Target NamePPIP5K1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PPIP5K1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species VIP1/ PPIP5K1/ HISPPD2A VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2260
    Target NamePPIP5K1
    Gene ID9677,327655,311355,710588,478276,101098233,510684,100070782
    Gene Symbol and SynonymsB430315C20Rik,HISPPD2A,hsVIP1,IP6K,IPS1,mKIAA0377,PPIP5K1,RGD1311552,VIP1
    Uniprot AccessionQ6PFW1,P0C644,A7Z050
    Uniprot Entry NameVIP1_HUMAN,VIP1_RAT,VIP1_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000168781
    Target ClassificationN/A

    The target: PPIP5K1, gene name: PPIP5K1, also named as HISPPD2A, IP6K, IPS1, VIP1, hsVIP1. This gene encodes a dual functional inositol kinase. The encoded enzyme converts inositol hexakisphosphate to diphosphoinositol pentakisphosphate and diphosphoinositol pentakisphosphate to bis-diphosphoinositol tetrakisphosphate. This protein may be important for intracellular signaling pathways. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 15.[provided by RefSeq, Jun 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.