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Anti-PRC2A/ PRRC2A/ BAT2 monoclonal antibody
Anti-PRC2A/ PRRC2A/ BAT2 antibody for FACS & in-vivo assay
Go to PRRC2A/PRRC2A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2269-Ab-1/ GM-Tg-hg-MP2269-Ab-2 | Anti-Human PRRC2A monoclonal antibody | Human |
| GM-Tg-rg-MP2269-Ab-1/ GM-Tg-rg-MP2269-Ab-2 | Anti-Rat PRRC2A monoclonal antibody | Rat |
| GM-Tg-mg-MP2269-Ab-1/ GM-Tg-mg-MP2269-Ab-2 | Anti-Mouse PRRC2A monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2269-Ab-1/ GM-Tg-cynog-MP2269-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PRRC2A monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2269-Ab-1/ GM-Tg-felg-MP2269-Ab-2 | Anti-Feline PRRC2A monoclonal antibody | Feline |
| GM-Tg-cang-MP2269-Ab-1/ GM-Tg-cang-MP2269-Ab-2 | Anti-Canine PRRC2A monoclonal antibody | Canine |
| GM-Tg-bovg-MP2269-Ab-1/ GM-Tg-bovg-MP2269-Ab-2 | Anti-Bovine PRRC2A monoclonal antibody | Bovine |
| GM-Tg-equg-MP2269-Ab-1/ GM-Tg-equg-MP2269-Ab-2 | Anti-Equine PRRC2A monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2269-Ab-1/ GM-Tg-hg-MP2269-Ab-2; GM-Tg-rg-MP2269-Ab-1/ GM-Tg-rg-MP2269-Ab-2; GM-Tg-mg-MP2269-Ab-1/ GM-Tg-mg-MP2269-Ab-2; GM-Tg-cynog-MP2269-Ab-1/ GM-Tg-cynog-MP2269-Ab-2; GM-Tg-felg-MP2269-Ab-1/ GM-Tg-felg-MP2269-Ab-2; GM-Tg-cang-MP2269-Ab-1/ GM-Tg-cang-MP2269-Ab-2; GM-Tg-bovg-MP2269-Ab-1/ GM-Tg-bovg-MP2269-Ab-2; GM-Tg-equg-MP2269-Ab-1/ GM-Tg-equg-MP2269-Ab-2 |
| Products Name | Anti-PRRC2A monoclonal antibody |
| Format | mab |
| Target Name | PRRC2A |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PRRC2A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species PRC2A/ PRRC2A/ BAT2 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP2269 |
| Target Name | PRRC2A |
| Gene ID | 7916,53761,294250,715715,481713,101085887,538553,100050226 |
| Gene Symbol and Synonyms | 3110039B05Rik,Bat-2,BAT2,D17H6S51E,D6S51,D6S51E,G2,mKIAA4178,PRRC2A,Wbp12 |
| Uniprot Accession | P48634,Q6MG48,Q5™26 |
| Uniprot Entry Name | PRC2A_HUMAN,PRC2A_MACMU,PRC2A_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000204469 |
| Target Classification | N/A |
The target: PRRC2A, gene name: PRRC2A, also named as BAT2, D6S51, D6S51E, G2. A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. This gene has microsatellite repeats which are associated with the age-at-onset of insulin-dependent diabetes mellitus (IDDM) and possibly thought to be involved with the inflammatory process of pancreatic beta-cell destruction during the development of IDDM. This gene is also a candidate gene for the development of rheumatoid arthritis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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