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Anti-RAB13/ GIG4 monoclonal antibody
Anti-RAB13/ GIG4 antibody for FACS & in-vivo assay
Go to RAB13/RAB13 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2273-Ab-1/ GM-Tg-hg-MP2273-Ab-2 | Anti-Human RAB13 monoclonal antibody | Human |
| GM-Tg-rg-MP2273-Ab-1/ GM-Tg-rg-MP2273-Ab-2 | Anti-Rat RAB13 monoclonal antibody | Rat |
| GM-Tg-mg-MP2273-Ab-1/ GM-Tg-mg-MP2273-Ab-2 | Anti-Mouse RAB13 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2273-Ab-1/ GM-Tg-cynog-MP2273-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RAB13 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2273-Ab-1/ GM-Tg-felg-MP2273-Ab-2 | Anti-Feline RAB13 monoclonal antibody | Feline |
| GM-Tg-cang-MP2273-Ab-1/ GM-Tg-cang-MP2273-Ab-2 | Anti-Canine RAB13 monoclonal antibody | Canine |
| GM-Tg-bovg-MP2273-Ab-1/ GM-Tg-bovg-MP2273-Ab-2 | Anti-Bovine RAB13 monoclonal antibody | Bovine |
| GM-Tg-equg-MP2273-Ab-1/ GM-Tg-equg-MP2273-Ab-2 | Anti-Equine RAB13 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2273-Ab-1/ GM-Tg-hg-MP2273-Ab-2; GM-Tg-rg-MP2273-Ab-1/ GM-Tg-rg-MP2273-Ab-2; GM-Tg-mg-MP2273-Ab-1/ GM-Tg-mg-MP2273-Ab-2; GM-Tg-cynog-MP2273-Ab-1/ GM-Tg-cynog-MP2273-Ab-2; GM-Tg-felg-MP2273-Ab-1/ GM-Tg-felg-MP2273-Ab-2; GM-Tg-cang-MP2273-Ab-1/ GM-Tg-cang-MP2273-Ab-2; GM-Tg-bovg-MP2273-Ab-1/ GM-Tg-bovg-MP2273-Ab-2; GM-Tg-equg-MP2273-Ab-1/ GM-Tg-equg-MP2273-Ab-2 |
| Products Name | Anti-RAB13 monoclonal antibody |
| Format | mab |
| Target Name | RAB13 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-RAB13 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species RAB13/ GIG4 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP2273 |
| Target Name | RAB13 |
| Gene ID | 5872,68328,81756,716156,612294,101099931,514541,100062377 |
| Gene Symbol and Synonyms | 0610007N03Rik,B230212B15Rik,GIG4,RAB13 |
| Uniprot Accession | P51153,P35286,F1PTE3,Q58DS5 |
| Uniprot Entry Name | RAB13_HUMAN,RAB13_RAT,RAB13_CANLF,RAB13_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Breast Cancer |
| Gene Ensembl | ENSG00000143545 |
| Target Classification | N/A |
The target: RAB13, gene name: RAB13, also named as GIG4. This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 12. [provided by RefSeq, Jan 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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