Anti-RND1/ ARHS/ RHO6 monoclonal antibody

Anti-RND1/ ARHS/ RHO6 antibody for FACS & in-vivo assay

Target products collectionGo to RND1/RND1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2304-Ab-1/ GM-Tg-hg-MP2304-Ab-2Anti-Human RND1 monoclonal antibodyHuman
GM-Tg-rg-MP2304-Ab-1/ GM-Tg-rg-MP2304-Ab-2Anti-Rat RND1 monoclonal antibodyRat
GM-Tg-mg-MP2304-Ab-1/ GM-Tg-mg-MP2304-Ab-2Anti-Mouse RND1 monoclonal antibodyMouse
GM-Tg-cynog-MP2304-Ab-1/ GM-Tg-cynog-MP2304-Ab-2Anti-Cynomolgus/ Rhesus macaque RND1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2304-Ab-1/ GM-Tg-felg-MP2304-Ab-2Anti-Feline RND1 monoclonal antibodyFeline
GM-Tg-cang-MP2304-Ab-1/ GM-Tg-cang-MP2304-Ab-2Anti-Canine RND1 monoclonal antibodyCanine
GM-Tg-bovg-MP2304-Ab-1/ GM-Tg-bovg-MP2304-Ab-2Anti-Bovine RND1 monoclonal antibodyBovine
GM-Tg-equg-MP2304-Ab-1/ GM-Tg-equg-MP2304-Ab-2Anti-Equine RND1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2304-Ab-1/ GM-Tg-hg-MP2304-Ab-2; GM-Tg-rg-MP2304-Ab-1/ GM-Tg-rg-MP2304-Ab-2;
GM-Tg-mg-MP2304-Ab-1/ GM-Tg-mg-MP2304-Ab-2; GM-Tg-cynog-MP2304-Ab-1/ GM-Tg-cynog-MP2304-Ab-2;
GM-Tg-felg-MP2304-Ab-1/ GM-Tg-felg-MP2304-Ab-2; GM-Tg-cang-MP2304-Ab-1/ GM-Tg-cang-MP2304-Ab-2;
GM-Tg-bovg-MP2304-Ab-1/ GM-Tg-bovg-MP2304-Ab-2; GM-Tg-equg-MP2304-Ab-1/ GM-Tg-equg-MP2304-Ab-2
Products NameAnti-RND1 monoclonal antibody
Formatmab
Target NameRND1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-RND1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species RND1/ ARHS/ RHO6 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP2304
    Target NameRND1
    Gene ID27289,223881,362993,710161,477623,101092619,508869,100058747
    Gene Symbol and SynonymsA830014L09Rik,ARHS,RHO6,RHOS,RND1
    Uniprot AccessionQ92730,Q2HJ68
    Uniprot Entry NameRND1_HUMAN,RND1_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000172602
    Target ClassificationN/A

    The target: RND1, gene name: RND1, also named as ARHS, RHO6, RHOS. This gene encodes a protein that belongs to the Rho GTPase family. Members of this family regulate the organization of the actin cytoskeleton in response to extracellular growth factors. A similar protein in rat interacts with a microtubule regulator to control axon extension. [provided by RefSeq, Apr 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.